| SP | Brown, K.Brown, Kevin # >> | 35 | 2000 | R | 91 | 23 | 23 | 11 | 7 | 3.03 | .262 | 1.04 | 7.1 | 2.3 | 8.0 | 157.2 | 124 | 53 | 53 | 19 | 40 | 139 | 1 | 0 | 0 | 1 | 17 | 4 | 2 | 3.64 |
| SP | Alvarez, W.Alvarez, Wilson # >> | 33 | 2003 | L | 73 | 22 | 22 | 3 | 9 | 5.59 | .349 | 1.59 | 11.2 | 3.1 | 7.1 | 93.1 | 116 | 61 | 58 | 16 | 32 | 73 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 4.76 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 55 | 22 | 22 | 7 | 10 | 7.01 | .377 | 1.78 | 12.7 | 3.4 | 6.2 | 119.1 | 168 | 100 | 93 | 28 | 45 | 82 | 0 | 0 | 0 | 0 | 7 | 4 | 1 | 5.92 |
| SP | Verlander, J.Verlander, Justin >> | 26 | 2009 | R | 43 | 21 | 21 | 6 | 8 | 5.86 | .352 | 1.60 | 10.4 | 4.0 | 8.8 | 138.1 | 159 | 92 | 90 | 32 | 62 | 135 | 1 | 0 | 0 | 0 | 6 | 4 | 3 | 5.49 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 91 | 56 | 0 | 1 | 3 | 3.95 | .281 | 1.16 | 6.7 | 3.7 | 6.6 | 82.0 | 61 | 38 | 36 | 15 | 34 | 60 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 5.20 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 65 | 60 | 0 | 2 | 2 | 3.57 | .307 | 1.29 | 7.7 | 4.1 | 6.3 | 80.2 | 68 | 35 | 32 | 11 | 36 | 56 | 0 | 7 | 3 | 0 | 0 | 3 | 4 | 4.85 |
| RP | Otsuka, A.Otsuka, Akinori >> | 32 | 2004 | R | 43 | 56 | 0 | 4 | 3 | 5.03 | .304 | 1.28 | 7.5 | 4.0 | 10.5 | 68.0 | 57 | 41 | 38 | 12 | 30 | 79 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 4.38 |
| RP | Aceves, A.Aceves, Alfredo † >> | 27 | 2009 | R | 28 | 45 | 0 | 7 | 1 | 3.47 | .284 | 1.14 | 8.4 | 2.0 | 6.6 | 59.2 | 55 | 25 | 23 | 5 | 13 | 43 | 0 | 5 | 2 | 0 | 0 | 3 | 0 | 3.46 |
| SP | Miller, W.Miller, Wade >> | 25 | 2001 | R | 28 | 2 | 1 | 0 | 1 | 9.00 | .400 | 1.83 | 16.5 | 0.0 | 7.5 | 6.0 | 11 | 6 | 6 | 2 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.17 |