| SP | Schilling, C.Schilling, Curt † >> | 36 | 2002 | R | 93 | 34 | 34 | 10 | 16 | 4.09 | .309 | 1.31 | 9.1 | 2.7 | 9.4 | 246.2 | 250 | 118 | 112 | 37 | 73 | 256 | 5 | 0 | 0 | 2 | 18 | 8 | 7 | 3.86 |
| SP | Millwood, K.Millwood, Kevin # >> | 28 | 2002 | R | 52 | 32 | 32 | 10 | 14 | 7.44 | .377 | 1.79 | 12.4 | 3.8 | 7.3 | 169.1 | 232 | 144 | 140 | 40 | 71 | 137 | 0 | 0 | 0 | 0 | 5 | 5 | 2 | 5.80 |
| SP | Burkett, J.Burkett, John # >> | 37 | 2001 | R | 50 | 32 | 32 | 11 | 12 | 5.30 | .321 | 1.38 | 9.6 | 2.8 | 7.4 | 190.1 | 203 | 117 | 112 | 41 | 60 | 157 | 2 | 0 | 0 | 2 | 13 | 7 | 6 | 5.21 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 91 | 0 | 6 | 4 | 2.03 | .240 | 0.92 | 6.2 | 2.1 | 9.1 | 133.1 | 91 | 30 | 30 | 11 | 31 | 134 | 0 | 5 | 6 | 0 | 0 | 4 | 2 | 2.85 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 73 | 86 | 0 | 3 | 3 | 5.26 | .325 | 1.43 | 9.8 | 3.2 | 9.7 | 102.2 | 111 | 60 | 60 | 20 | 36 | 110 | 0 | 6 | 4 | 0 | 0 | 1 | 4 | 4.48 |
| RP | Mota, G.Mota, Guillermo >> | 30 | 2003 | R | 50 | 69 | 0 | 6 | 4 | 4.22 | .304 | 1.27 | 8.6 | 2.8 | 6.1 | 96.0 | 92 | 47 | 45 | 13 | 30 | 65 | 0 | 7 | 3 | 0 | 0 | 4 | 0 | 4.47 |
| RP | Donnelly, B.Donnelly, Brendan >> | 32 | 2003 | R | 40 | 59 | 0 | 7 | 3 | 5.15 | .328 | 1.42 | 9.1 | 3.8 | 10.6 | 71.2 | 72 | 43 | 41 | 9 | 30 | 84 | 0 | 7 | 2 | 0 | 0 | 3 | 1 | 3.68 |
| RP | Stewart, S.Stewart, Scott >> | 27 | 2002 | L | 29 | 49 | 0 | 2 | 0 | 3.75 | .324 | 1.42 | 9.6 | 3.3 | 8.5 | 57.2 | 61 | 25 | 24 | 4 | 21 | 54 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 3.18 |