| SP | Clemens, R.Clemens, Roger # >> | 43 | 2005 | R | 94 | 11 | 11 | 6 | 3 | 3.57 | .261 | 1.03 | 7.0 | 2.3 | 7.4 | 68.0 | 53 | 30 | 27 | 14 | 17 | 56 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | 4.87 |
| SP | Carpenter, C.Carpenter, Chris >> | 34 | 2009 | R | 80 | 11 | 11 | 5 | 4 | 5.20 | .315 | 1.38 | 9.8 | 2.7 | 6.5 | 71.0 | 77 | 41 | 41 | 9 | 21 | 51 | 2 | 0 | 0 | 1 | 6 | 0 | 1 | 4.10 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 67 | 11 | 11 | 3 | 6 | 5.12 | .323 | 1.40 | 9.6 | 3.0 | 5.7 | 65.0 | 69 | 39 | 37 | 13 | 22 | 41 | 1 | 0 | 0 | 0 | 6 | 2 | 2 | 5.45 |
| SP | Harang, A.Harang, Aaron >> | 29 | 2007 | R | 51 | 10 | 10 | 1 | 4 | 7.09 | .387 | 1.88 | 11.5 | 5.4 | 6.5 | 53.1 | 68 | 46 | 42 | 10 | 32 | 38 | 0 | 0 | 0 | 0 | 3 | 1 | 2 | 5.89 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 80 | 26 | 0 | 1 | 1 | 3.57 | .274 | 1.13 | 5.9 | 4.4 | 11.1 | 35.1 | 23 | 14 | 14 | 5 | 17 | 43 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 3.86 |
| RP | Cormier, R.Cormier, Rheal >> | 36 | 2003 | L | 63 | 19 | 0 | 3 | 1 | 2.77 | .278 | 1.15 | 6.9 | 3.5 | 6.2 | 26.0 | 20 | 8 | 8 | 3 | 10 | 18 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.27 |
| RP | Aardsma, D.Aardsma, David >> | 28 | 2009 | R | 38 | 14 | 0 | 0 | 1 | 7.15 | .346 | 1.59 | 7.4 | 7.4 | 10.6 | 11.1 | 9 | 9 | 9 | 3 | 9 | 13 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 6.64 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 48 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |