| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 11 | 11 | 1 | 3 | 3.00 | .271 | 1.10 | 6.5 | 3.4 | 10.2 | 51.0 | 37 | 18 | 17 | 8 | 19 | 58 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.94 |
| SP | Weaver, J.Weaver, Jered # >> | 24 | 2006 | R | 83 | 11 | 11 | 5 | 4 | 4.86 | .303 | 1.25 | 8.3 | 3.0 | 6.5 | 76.0 | 70 | 47 | 41 | 12 | 25 | 55 | 0 | 0 | 0 | 0 | 5 | 4 | 2 | 4.75 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 70 | 10 | 10 | 5 | 2 | 2.97 | .328 | 1.45 | 9.2 | 4.1 | 7.7 | 60.2 | 61 | 20 | 20 | 8 | 27 | 51 | 0 | 0 | 0 | 0 | 6 | 1 | 4 | 4.43 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 60 | 10 | 10 | 2 | 5 | 5.63 | .351 | 1.61 | 11.3 | 3.3 | 6.5 | 72.0 | 90 | 48 | 45 | 11 | 26 | 52 | 1 | 0 | 0 | 0 | 3 | 1 | 0 | 4.67 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 86 | 25 | 0 | 1 | 5 | 4.26 | .321 | 1.39 | 5.5 | 7.3 | 9.6 | 31.2 | 19 | 23 | 15 | 3 | 25 | 33 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 4.65 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 72 | 23 | 0 | 3 | 0 | 1.98 | .274 | 1.13 | 7.0 | 3.3 | 3.7 | 27.1 | 21 | 6 | 6 | 2 | 10 | 11 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 4.26 |
| RP | Masset, N.Masset, Nick >> | 27 | 2009 | R | 47 | 17 | 0 | 2 | 0 | 3.71 | .378 | 1.82 | 10.1 | 6.4 | 5.8 | 17.0 | 19 | 7 | 7 | 3 | 12 | 11 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 6.12 |
| SP | Burnett, A.Burnett, A.J. >> | 25 | 2002 | R | 57 | 8 | 0 | 0 | 2 | 4.50 | .314 | 1.38 | 7.9 | 4.5 | 6.2 | 16.0 | 14 | 8 | 8 | 0 | 8 | 11 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.13 |