| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 77 | 7 | 7 | 3 | 2 | 2.80 | .308 | 1.31 | 7.8 | 4.0 | 9.2 | 45.0 | 39 | 15 | 14 | 1 | 20 | 46 | 0 | 0 | 0 | 0 | 5 | 1 | 0 | 2.64 |
| SP | Weaver, J.Weaver, Jered >> | 24 | 2006 | R | 83 | 7 | 7 | 1 | 3 | 3.94 | .327 | 1.46 | 8.4 | 4.7 | 6.9 | 48.0 | 45 | 21 | 21 | 5 | 25 | 37 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 4.38 |
| SP | Maddux, G.Maddux, Greg # >> | 34 | 2000 | R | 57 | 6 | 6 | 2 | 4 | 4.46 | .309 | 1.31 | 8.6 | 3.4 | 7.4 | 40.1 | 38 | 20 | 20 | 9 | 15 | 33 | 1 | 0 | 0 | 0 | 2 | 1 | 1 | 5.48 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 68 | 6 | 4 | 1 | 1 | 5.45 | .331 | 1.48 | 10.9 | 2.5 | 7.9 | 33.0 | 40 | 22 | 20 | 7 | 9 | 29 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 4.82 |
| SP | Wakefield, T.Wakefield, Tim >> | 36 | 2002 | R | 86 | 6 | 6 | 0 | 3 | 6.75 | .385 | 1.88 | 9.9 | 7.3 | 7.7 | 21.1 | 23 | 16 | 16 | 4 | 17 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 6.19 |
| CL | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 85 | 10 | 0 | 1 | 0 | 0.77 | .314 | 1.37 | 10.6 | 2.5 | 9.8 | 11.2 | 13 | 1 | 1 | 0 | 3 | 12 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 1.64 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 65 | 14 | 0 | 2 | 1 | 3.94 | .314 | 1.25 | 8.4 | 2.8 | 6.2 | 16.0 | 15 | 8 | 7 | 0 | 5 | 11 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 2.94 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 83 | 13 | 0 | 1 | 1 | 5.79 | .333 | 1.50 | 10.3 | 3.2 | 10.3 | 14.0 | 16 | 9 | 9 | 3 | 5 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 4.57 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 100 | 14 | 0 | 1 | 0 | 6.57 | .275 | 1.14 | 7.5 | 3.0 | 11.3 | 12.1 | 10 | 9 | 9 | 2 | 4 | 15 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.67 |
| SP | Hernandez, F.Hernandez, Felix >> | 19 | 2005 | R | 96 | 6 | 3 | 1 | 1 | 11.91 | .456 | 2.38 | 18.0 | 4.1 | 6.5 | 22.2 | 44 | 30 | 30 | 3 | 10 | 16 | 0 | 0 | 0 | 0 | 1 | 3 | 0 | 5.09 |