| SP | Schmidt, J.Schmidt, Jason † >> | 30 | 2003 | R | 99 | 23 | 23 | 13 | 7 | 3.05 | .278 | 1.13 | 7.3 | 2.9 | 10.1 | 165.1 | 133 | 62 | 56 | 15 | 53 | 186 | 7 | 0 | 0 | 5 | 16 | 5 | 2 | 2.98 |
| SP | Peavy, J.Peavy, Jake † >> | 26 | 2007 | R | 88 | 22 | 22 | 10 | 5 | 3.97 | .293 | 1.20 | 7.2 | 3.6 | 8.6 | 149.2 | 120 | 70 | 66 | 22 | 59 | 143 | 2 | 0 | 0 | 1 | 13 | 7 | 0 | 4.33 |
| SP | Hamels, C.Hamels, Cole # >> | 25 | 2008 | L | 72 | 22 | 22 | 8 | 9 | 5.83 | .349 | 1.55 | 10.3 | 3.6 | 7.2 | 122.0 | 140 | 80 | 79 | 28 | 49 | 97 | 0 | 0 | 0 | 0 | 8 | 7 | 0 | 5.77 |
| SP | Loaiza, E.Loaiza, Esteban >> | 32 | 2003 | R | 58 | 23 | 21 | 8 | 6 | 6.43 | .357 | 1.66 | 10.4 | 4.5 | 6.6 | 113.1 | 131 | 85 | 81 | 25 | 57 | 83 | 0 | 0 | 0 | 0 | 7 | 1 | 4 | 5.95 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 75 | 41 | 0 | 6 | 2 | 2.68 | .267 | 1.07 | 7.2 | 2.5 | 7.9 | 50.1 | 40 | 15 | 15 | 6 | 14 | 44 | 0 | 3 | 0 | 0 | 0 | 1 | 3 | 3.70 |
| RP | Thornton, M.Thornton, Matt >> | 32 | 2008 | L | 53 | 54 | 0 | 3 | 1 | 4.91 | .313 | 1.36 | 8.5 | 3.8 | 10.1 | 55.0 | 52 | 30 | 30 | 14 | 23 | 62 | 0 | 9 | 2 | 0 | 0 | 0 | 2 | 5.31 |