| SP | Perez, O.Perez, Oliver # >> | 23 | 2004 | L | 75 | 30 | 30 | 14 | 11 | 4.51 | .310 | 1.33 | 8.6 | 3.4 | 9.2 | 193.2 | 185 | 102 | 97 | 25 | 73 | 198 | 1 | 0 | 0 | 1 | 15 | 3 | 3 | 3.81 |
| SP | Nolasco, R.Nolasco, Ricky # >> | 26 | 2008 | R | 55 | 30 | 30 | 8 | 18 | 7.39 | .383 | 1.83 | 13.3 | 3.2 | 7.0 | 164.1 | 242 | 143 | 135 | 33 | 58 | 127 | 0 | 0 | 0 | 0 | 7 | 6 | 1 | 5.24 |
| SP | Santana, E.Santana, Ervin >> | 25 | 2008 | R | 54 | 29 | 29 | 9 | 7 | 5.13 | .343 | 1.54 | 10.6 | 3.3 | 7.0 | 175.1 | 206 | 103 | 100 | 27 | 64 | 136 | 0 | 0 | 0 | 0 | 12 | 5 | 0 | 4.63 |
| SP | Johnson, J.Johnson, Josh >> | 25 | 2009 | R | 46 | 27 | 27 | 12 | 9 | 5.73 | .347 | 1.56 | 10.4 | 3.7 | 6.8 | 169.2 | 196 | 109 | 108 | 30 | 69 | 127 | 1 | 0 | 0 | 1 | 8 | 5 | 7 | 5.12 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 90 | 76 | 0 | 5 | 1 | 4.76 | .333 | 1.46 | 9.1 | 4.1 | 11.0 | 92.2 | 93 | 50 | 49 | 15 | 42 | 112 | 0 | 5 | 3 | 0 | 0 | 4 | 2 | 4.18 |
| RP | Thornton, M.Thornton, Matt >> | 32 | 2008 | L | 53 | 75 | 0 | 0 | 1 | 3.74 | .287 | 1.20 | 7.2 | 3.7 | 9.0 | 98.2 | 78 | 42 | 41 | 10 | 40 | 98 | 0 | 8 | 2 | 0 | 0 | 1 | 4 | 3.58 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 37 | 65 | 0 | 2 | 9 | 4.74 | .351 | 1.59 | 9.0 | 5.4 | 8.9 | 74.0 | 74 | 40 | 39 | 7 | 44 | 73 | 0 | 10 | 2 | 0 | 0 | 2 | 5 | 4.12 |
| RP | Corpas, M.Corpas, Manuel >> | 25 | 2007 | R | 23 | 55 | 0 | 7 | 2 | 3.08 | .295 | 1.26 | 8.6 | 2.8 | 6.3 | 61.1 | 58 | 21 | 21 | 10 | 19 | 43 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 4.66 |
| RP | Romero, J.Romero, J.C. >> | 26 | 2002 | L | 12 | 36 | 0 | 1 | 2 | 7.42 | .409 | 2.08 | 11.4 | 7.5 | 9.3 | 30.1 | 38 | 25 | 25 | 7 | 25 | 31 | 0 | 4 | 0 | 0 | 0 | 0 | 2 | 6.47 |
| SP | Volquez, E.Volquez, Edinson >> | 25 | 2008 | R | 24 | 1 | 0 | 1 | 0 | 0.00 | .500 | 3.00 | - | - | - | 0.1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Dempster, R.Dempster, Ryan >> | 31 | 2008 | R | 38 | 18 | 1 | 1 | 0 | 4.02 | .329 | 1.44 | 9.0 | 4.1 | 9.0 | 31.1 | 31 | 14 | 14 | 6 | 14 | 31 | 0 | 3 | 0 | 0 | 1 | 1 | 1 | 4.97 |