| SP | Schilling, C.Schilling, Curt # >> | 36 | 2002 | R | 93 | 15 | 15 | 8 | 5 | 3.95 | .273 | 1.09 | 8.8 | 1.1 | 8.5 | 111.2 | 109 | 52 | 49 | 19 | 13 | 105 | 3 | 0 | 0 | 1 | 7 | 4 | 2 | 3.79 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 55 | 15 | 15 | 4 | 8 | 6.06 | .347 | 1.55 | 12.1 | 1.9 | 5.0 | 84.2 | 113 | 57 | 57 | 18 | 18 | 47 | 0 | 0 | 0 | 0 | 5 | 4 | 1 | 5.45 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 49 | 14 | 14 | 5 | 7 | 5.82 | .333 | 1.48 | 10.2 | 3.1 | 7.0 | 82.0 | 93 | 54 | 53 | 13 | 28 | 64 | 3 | 0 | 0 | 1 | 5 | 2 | 2 | 4.60 |
| SP | Jimenez, U.Jimenez, Ubaldo | 25 | 2009 | R | 36 | 14 | 14 | 6 | 5 | 4.42 | .314 | 1.37 | 8.8 | 3.6 | 6.4 | 89.2 | 87 | 44 | 44 | 14 | 36 | 63 | 2 | 0 | 0 | 1 | 9 | 0 | 1 | 4.84 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 37 | 0 | 4 | 1 | 2.44 | .258 | 1.03 | 6.9 | 2.5 | 10.2 | 51.2 | 39 | 19 | 14 | 6 | 14 | 58 | 0 | 3 | 3 | 0 | 0 | 1 | 1 | 3.14 |
| RP | Timlin, M.Timlin, Mike >> | 36 | 2002 | R | 50 | 29 | 0 | 2 | 1 | 3.43 | .285 | 1.19 | 9.5 | 1.4 | 5.8 | 39.1 | 41 | 18 | 15 | 3 | 6 | 25 | 0 | 6 | 1 | 0 | 0 | 0 | 1 | 3.18 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 37 | 17 | 0 | 3 | 0 | 0.81 | .221 | 0.81 | 3.7 | 3.7 | 10.6 | 22.1 | 9 | 2 | 2 | 1 | 9 | 26 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 2.59 |