| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 31 | 31 | 9 | 11 | 4.94 | .322 | 1.40 | 8.3 | 4.3 | 9.0 | 184.0 | 170 | 108 | 101 | 24 | 87 | 184 | 0 | 0 | 0 | 0 | 11 | 5 | 2 | 4.20 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 86 | 30 | 30 | 9 | 16 | 4.95 | .334 | 1.49 | 10.6 | 2.9 | 7.4 | 214.1 | 252 | 122 | 118 | 30 | 68 | 175 | 6 | 0 | 0 | 1 | 13 | 3 | 3 | 4.18 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 45 | 31 | 29 | 12 | 11 | 5.84 | .350 | 1.55 | 10.5 | 3.5 | 6.3 | 186.1 | 216 | 129 | 121 | 26 | 73 | 130 | 2 | 0 | 0 | 1 | 9 | 12 | 6 | 4.79 |
| RP | Papelbon, J.Papelbon, Jonathan † >> | 26 | 2006 | R | 93 | 94 | 0 | 10 | 5 | 2.64 | .274 | 1.11 | 7.7 | 2.3 | 9.7 | 136.1 | 116 | 40 | 40 | 14 | 35 | 146 | 0 | 9 | 4 | 0 | 0 | 3 | 3 | 3.03 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 84 | 0 | 8 | 4 | 2.85 | .297 | 1.23 | 6.5 | 4.7 | 9.2 | 110.1 | 79 | 35 | 35 | 9 | 57 | 112 | 0 | 10 | 1 | 0 | 0 | 4 | 4 | 3.69 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 73 | 69 | 0 | 5 | 4 | 3.36 | .293 | 1.22 | 8.4 | 2.7 | 9.0 | 88.1 | 82 | 43 | 33 | 14 | 26 | 88 | 0 | 10 | 4 | 0 | 0 | 2 | 0 | 4.02 |