| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 99 | 13 | 13 | 7 | 5 | 3.18 | .300 | 1.25 | 8.7 | 2.5 | 10.0 | 99.0 | 96 | 38 | 35 | 20 | 28 | 110 | 0 | 0 | 0 | 0 | 9 | 3 | 3 | 4.34 |
| SP | Duchscherer, J.Duchscherer, Justin # >> | 31 | 2008 | R | 84 | 13 | 13 | 4 | 4 | 4.77 | .305 | 1.32 | 9.4 | 2.6 | 6.0 | 88.2 | 92 | 48 | 47 | 13 | 25 | 59 | 0 | 0 | 0 | 0 | 7 | 0 | 3 | 4.43 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 67 | 13 | 13 | 7 | 5 | 4.12 | .290 | 1.18 | 8.5 | 2.2 | 5.6 | 89.2 | 84 | 41 | 41 | 14 | 22 | 55 | 2 | 0 | 0 | 0 | 8 | 4 | 3 | 4.69 |
| SP | Millwood, K.Millwood, Kevin >> | 28 | 2002 | R | 52 | 12 | 12 | 5 | 4 | 5.40 | .340 | 1.51 | 9.4 | 4.2 | 6.6 | 75.0 | 78 | 46 | 45 | 17 | 35 | 55 | 1 | 0 | 0 | 0 | 4 | 3 | 1 | 6.00 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 35 | 0 | 2 | 2 | 4.05 | .340 | 1.48 | 9.0 | 4.5 | 7.8 | 46.2 | 46 | 22 | 21 | 5 | 23 | 40 | 0 | 7 | 4 | 0 | 0 | 3 | 0 | 4.37 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 86 | 33 | 0 | 2 | 2 | 5.13 | .367 | 1.74 | 7.9 | 7.9 | 8.2 | 33.1 | 29 | 19 | 19 | 6 | 29 | 30 | 0 | 6 | 1 | 0 | 0 | 0 | 3 | 6.18 |
| RP | Mota, G.Mota, Guillermo >> | 30 | 2003 | R | 50 | 16 | 0 | 1 | 0 | 5.64 | .330 | 1.43 | 9.8 | 3.3 | 5.3 | 22.1 | 24 | 16 | 14 | 5 | 8 | 13 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 6.00 |
| SP | Verlander, J.Verlander, Justin >> | 26 | 2009 | R | 42 | 1 | 0 | 0 | 0 | 0.00 | .500 | 3.00 | - | - | - | 0.2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Johnson, J.Johnson, Josh >> | 25 | 2009 | R | 47 | 9 | 0 | 1 | 3 | 7.98 | .362 | 1.64 | 11.6 | 3.9 | 6.4 | 14.2 | 18 | 13 | 13 | 4 | 6 | 10 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 6.79 |