| SP | Loaiza, E.Loaiza, Esteban # $ >> | 32 | 2003 | R | 60 | 12 | 12 | 6 | 3 | 3.98 | .289 | 1.19 | 7.8 | 3.0 | 7.9 | 81.1 | 70 | 36 | 36 | 8 | 27 | 71 | 1 | 0 | 0 | 1 | 8 | 2 | 2 | 3.60 |
| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 13 | 13 | 6 | 3 | 4.08 | .282 | 1.15 | 8.0 | 2.4 | 8.3 | 92.2 | 82 | 42 | 42 | 7 | 25 | 85 | 4 | 0 | 0 | 0 | 9 | 2 | 1 | 3.02 |
| SP | Maddux, G.Maddux, Greg # >> | 34 | 2000 | R | 58 | 13 | 12 | 6 | 4 | 5.84 | .327 | 1.42 | 10.6 | 2.1 | 6.4 | 77.0 | 91 | 53 | 50 | 18 | 18 | 55 | 1 | 0 | 0 | 1 | 4 | 3 | 0 | 5.43 |
| SP | Weaver, J.Weaver, Jered # >> | 24 | 2006 | R | 83 | 12 | 12 | 4 | 3 | 6.58 | .362 | 1.66 | 10.6 | 4.3 | 7.3 | 67.0 | 79 | 49 | 49 | 19 | 32 | 54 | 0 | 0 | 0 | 0 | 4 | 3 | 0 | 6.64 |
| CL | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 87 | 24 | 0 | 1 | 1 | 1.09 | .149 | 0.53 | 3.8 | 1.1 | 9.8 | 24.2 | 10 | 3 | 3 | 3 | 3 | 26 | 0 | 12 | 1 | 0 | 0 | 0 | 0 | 2.83 |
| SU | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 14 | 0 | 0 | 2 | 2.14 | .232 | 0.90 | 7.3 | 0.9 | 8.6 | 21.0 | 17 | 5 | 5 | 2 | 2 | 20 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 2.62 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 72 | 15 | 0 | 1 | 0 | 3.12 | .288 | 1.21 | 6.9 | 4.2 | 7.4 | 17.1 | 13 | 6 | 6 | 1 | 8 | 14 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.53 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 78 | 18 | 0 | 1 | 0 | 4.86 | .315 | 1.38 | 10.1 | 2.8 | 9.6 | 16.2 | 18 | 10 | 9 | 4 | 5 | 17 | 0 | 6 | 1 | 0 | 0 | 0 | 0 | 5.06 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 89 | 9 | 0 | 1 | 0 | 6.23 | .257 | 0.92 | 7.9 | 1.1 | 10.1 | 8.2 | 7 | 6 | 6 | 3 | 1 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.38 |
| SP | Williams, W.Williams, Woody # >> | 36 | 2002 | R | 79 | 10 | 3 | 1 | 3 | 7.78 | .413 | 2.08 | 14.4 | 4.4 | 5.1 | 37.0 | 59 | 36 | 32 | 8 | 18 | 21 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.22 |