| SP | Brown, K.Brown, Kevin † # >> | 35 | 2000 | R | 91 | 19 | 19 | 10 | 5 | 2.55 | .244 | 0.91 | 6.7 | 1.5 | 9.0 | 130.1 | 97 | 39 | 37 | 13 | 22 | 130 | 0 | 0 | 0 | 0 | 15 | 7 | 0 | 2.97 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 86 | 18 | 18 | 6 | 9 | 5.25 | .313 | 1.34 | 9.6 | 2.5 | 7.3 | 128.2 | 136 | 76 | 75 | 21 | 36 | 104 | 2 | 0 | 0 | 0 | 8 | 4 | 0 | 4.45 |
| SP | Johnson, J.Johnson, Josh >> | 25 | 2009 | R | 46 | 17 | 17 | 9 | 2 | 4.64 | .339 | 1.51 | 9.6 | 4.1 | 6.3 | 108.2 | 115 | 58 | 56 | 13 | 49 | 75 | 1 | 0 | 0 | 0 | 9 | 3 | 4 | 4.62 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 49 | 0 | 3 | 2 | 4.74 | .317 | 1.38 | 9.1 | 3.3 | 7.7 | 68.1 | 69 | 38 | 36 | 10 | 25 | 58 | 0 | 1 | 3 | 0 | 0 | 1 | 2 | 4.35 |
| RP | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 48 | 42 | 0 | 1 | 5 | 6.04 | .356 | 1.61 | 10.6 | 4.1 | 8.0 | 44.2 | 52 | 30 | 30 | 9 | 20 | 39 | 0 | 7 | 1 | 0 | 0 | 2 | 0 | 5.39 |
| RP | Kim, B.Kim, Byung-Hyun >> | 23 | 2002 | R | 32 | 25 | 0 | 0 | 1 | 6.26 | .349 | 1.57 | 8.7 | 5.7 | 11.3 | 27.1 | 26 | 19 | 19 | 4 | 17 | 34 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 4.41 |
| RP | Seanez, R.Seanez, Rudy >> | 37 | 2005 | R | 21 | 23 | 0 | 0 | 2 | 8.10 | .386 | 1.84 | 12.9 | 3.9 | 10.6 | 23.1 | 33 | 22 | 21 | 5 | 10 | 27 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.91 |
| SP | Washburn, J.Washburn, Jarrod >> | 28 | 2002 | L | 31 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |