| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 20 | 20 | 5 | 7 | 3.96 | .323 | 1.40 | 8.2 | 4.4 | 9.2 | 120.1 | 109 | 64 | 53 | 21 | 59 | 123 | 0 | 0 | 0 | 0 | 9 | 4 | 2 | 4.80 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 72 | 20 | 20 | 5 | 7 | 7.35 | .355 | 1.61 | 10.3 | 4.1 | 7.4 | 109.0 | 125 | 94 | 89 | 25 | 50 | 90 | 0 | 0 | 0 | 0 | 7 | 5 | 0 | 5.84 |
| SP | Maddux, G.Maddux, Greg >> | 34 | 2000 | R | 58 | 19 | 19 | 6 | 6 | 5.74 | .340 | 1.54 | 10.9 | 3.0 | 7.3 | 125.1 | 152 | 83 | 80 | 17 | 41 | 102 | 3 | 0 | 0 | 1 | 9 | 1 | 1 | 4.14 |
| SP | Nolasco, R.Nolasco, Ricky # >> | 26 | 2008 | R | 56 | 19 | 19 | 4 | 7 | 5.59 | .326 | 1.41 | 9.9 | 2.8 | 7.1 | 114.1 | 125 | 71 | 71 | 20 | 36 | 90 | 0 | 0 | 0 | 0 | 10 | 5 | 3 | 4.78 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 51 | 0 | 4 | 1 | 4.17 | .306 | 1.31 | 7.8 | 4.1 | 10.1 | 73.1 | 63 | 34 | 34 | 10 | 33 | 82 | 0 | 3 | 3 | 0 | 0 | 1 | 3 | 3.93 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 76 | 52 | 0 | 6 | 2 | 3.74 | .272 | 1.08 | 6.9 | 2.8 | 8.5 | 79.1 | 61 | 34 | 33 | 13 | 25 | 75 | 0 | 3 | 2 | 0 | 0 | 3 | 0 | 4.30 |
| RP | Thornton, M.Thornton, Matt >> | 32 | 2008 | L | 54 | 45 | 0 | 4 | 5 | 5.02 | .325 | 1.45 | 9.5 | 3.6 | 8.2 | 57.1 | 60 | 32 | 32 | 9 | 23 | 52 | 0 | 3 | 3 | 0 | 0 | 0 | 5 | 4.44 |
| RP | Hawkins, L.Hawkins, LaTroy >> | 30 | 2002 | R | 40 | 42 | 0 | 5 | 2 | 6.35 | .390 | 1.90 | 13.2 | 4.0 | 6.8 | 45.1 | 66 | 33 | 32 | 8 | 20 | 34 | 0 | 1 | 3 | 0 | 0 | 1 | 1 | 5.20 |