| SP | Johnson, R.Johnson, Randy >> | 38 | 2001 | L | 97 | 19 | 19 | 7 | 7 | 3.18 | .292 | 1.23 | 7.7 | 3.4 | 10.4 | 141.1 | 120 | 54 | 50 | 12 | 54 | 163 | 1 | 0 | 0 | 0 | 13 | 1 | 4 | 2.96 |
| SP | Perez, O.Perez, Oliver >> | 23 | 2004 | L | 75 | 17 | 17 | 8 | 7 | 4.02 | .298 | 1.25 | 7.4 | 3.9 | 8.7 | 116.1 | 95 | 54 | 52 | 20 | 50 | 112 | 1 | 0 | 0 | 0 | 10 | 3 | 3 | 4.68 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 70 | 17 | 17 | 6 | 2 | 5.05 | .311 | 1.32 | 9.1 | 2.8 | 5.9 | 103.1 | 104 | 58 | 58 | 24 | 32 | 67 | 0 | 0 | 0 | 0 | 7 | 4 | 5 | 5.78 |
| SP | Santana, E.Santana, Ervin >> | 25 | 2008 | R | 54 | 17 | 17 | 6 | 8 | 6.40 | .353 | 1.61 | 12.1 | 2.5 | 6.4 | 102.2 | 137 | 74 | 73 | 26 | 28 | 72 | 0 | 0 | 0 | 0 | 6 | 3 | 3 | 5.81 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 100 | 51 | 0 | 0 | 7 | 4.76 | .311 | 1.32 | 8.7 | 3.2 | 9.8 | 64.1 | 62 | 34 | 34 | 9 | 23 | 70 | 0 | 6 | 1 | 0 | 0 | 2 | 0 | 3.81 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 85 | 46 | 0 | 5 | 2 | 3.86 | .303 | 1.30 | 6.5 | 5.4 | 8.3 | 53.2 | 38 | 24 | 23 | 10 | 32 | 49 | 0 | 6 | 5 | 0 | 0 | 0 | 2 | 5.42 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 71 | 35 | 0 | 4 | 0 | 3.83 | .294 | 1.23 | 6.8 | 4.3 | 10.1 | 40.0 | 30 | 17 | 17 | 3 | 19 | 45 | 0 | 5 | 2 | 0 | 0 | 1 | 1 | 3.23 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 55 | 28 | 0 | 4 | 0 | 3.95 | .293 | 1.17 | 6.7 | 4.0 | 8.7 | 27.1 | 20 | 12 | 12 | 3 | 12 | 26 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 4.07 |
| RP | Linebrink, S.Linebrink, Scott >> | 28 | 2004 | R | 44 | 19 | 0 | 1 | 0 | 6.10 | .354 | 1.50 | 10.4 | 3.6 | 6.3 | 20.2 | 23 | 14 | 14 | 4 | 8 | 14 | 0 | 3 | 0 | 0 | 0 | 3 | 1 | 5.85 |
| SP | Verlander, J.Verlander, Justin >> | 26 | 2009 | R | 43 | 5 | 0 | 1 | 1 | 7.84 | .404 | 1.94 | 9.0 | 9.0 | 9.0 | 10.1 | 10 | 9 | 9 | 2 | 10 | 10 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 6.90 |