| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 20 | 20 | 5 | 6 | 4.39 | .313 | 1.30 | 8.4 | 3.3 | 7.2 | 112.2 | 105 | 57 | 55 | 13 | 41 | 89 | 0 | 0 | 0 | 0 | 13 | 8 | 0 | 4.23 |
| SP | Alvarez, W.Alvarez, Wilson >> | 33 | 2003 | L | 73 | 20 | 20 | 4 | 6 | 5.10 | .322 | 1.40 | 10.8 | 1.7 | 6.6 | 83.0 | 100 | 52 | 47 | 14 | 16 | 61 | 0 | 0 | 0 | 0 | 4 | 2 | 2 | 4.37 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 70 | 20 | 17 | 6 | 7 | 4.61 | .331 | 1.44 | 8.6 | 4.5 | 6.6 | 97.2 | 93 | 55 | 50 | 13 | 48 | 71 | 0 | 0 | 0 | 0 | 7 | 4 | 4 | 4.89 |
| RP | Farnsworth, K.Farnsworth, Kyle >> | 25 | 2001 | R | 22 | 55 | 0 | 1 | 0 | 4.07 | .304 | 1.31 | 8.3 | 3.5 | 10.8 | 66.1 | 61 | 34 | 30 | 7 | 26 | 79 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.17 |
| CL | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 56 | 0 | 2 | 6 | 4.52 | .323 | 1.42 | 10.1 | 2.8 | 8.2 | 65.2 | 73 | 33 | 33 | 10 | 20 | 59 | 0 | 20 | 2 | 0 | 0 | 1 | 0 | 4.15 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 71 | 50 | 0 | 3 | 3 | 3.73 | .314 | 1.33 | 8.3 | 3.8 | 9.9 | 60.1 | 55 | 26 | 25 | 3 | 25 | 66 | 0 | 0 | 2 | 0 | 0 | 3 | 6 | 2.85 |