| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 100 | 38 | 38 | 21 | 11 | 3.76 | .283 | 1.15 | 7.7 | 2.7 | 9.3 | 246.1 | 210 | 108 | 103 | 31 | 73 | 255 | 3 | 0 | 0 | 2 | 23 | 8 | 3 | 3.55 |
| SP | Vazquez, J.Vazquez, Javier † # >> | 33 | 2009 | R | 87 | 36 | 36 | 22 | 9 | 4.24 | .294 | 1.23 | 8.4 | 2.7 | 9.3 | 242.0 | 225 | 120 | 114 | 32 | 73 | 251 | 4 | 0 | 0 | 3 | 20 | 4 | 7 | 3.60 |
| SP | Haren, D.Haren, Dan $$ >> | 29 | 2009 | R | 85 | 34 | 34 | 11 | 8 | 4.47 | .319 | 1.37 | 9.6 | 2.7 | 7.1 | 207.1 | 221 | 106 | 103 | 31 | 63 | 164 | 1 | 0 | 0 | 1 | 19 | 7 | 9 | 4.38 |
| SP | Greinke, Z.Greinke, Zack >> | 26 | 2009 | R | 76 | 34 | 34 | 15 | 8 | 4.36 | .313 | 1.32 | 9.3 | 2.6 | 8.7 | 202.1 | 209 | 99 | 98 | 24 | 59 | 196 | 0 | 0 | 0 | 0 | 18 | 8 | 2 | 3.60 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 72 | 97 | 0 | 4 | 3 | 2.76 | .271 | 1.09 | 7.6 | 2.2 | 7.0 | 111.0 | 94 | 39 | 34 | 13 | 27 | 86 | 0 | 2 | 2 | 0 | 0 | 3 | 1 | 3.78 |
| CL | Rivera, M.Rivera, Mariano † $$ >> | 39 | 2008 | R | 96 | 86 | 0 | 7 | 8 | 2.72 | .282 | 1.15 | 7.6 | 2.7 | 8.5 | 96.0 | 81 | 32 | 29 | 8 | 29 | 91 | 0 | 41 | 6 | 0 | 0 | 3 | 0 | 3.19 |
| SU | Wagner, B.Wagner, Billy >> | 32 | 2003 | L | 89 | 90 | 0 | 2 | 2 | 3.30 | .293 | 1.20 | 7.3 | 3.5 | 9.0 | 92.2 | 75 | 38 | 34 | 12 | 36 | 92 | 0 | 4 | 6 | 0 | 0 | 4 | 6 | 4.00 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 65 | 77 | 0 | 5 | 1 | 2.79 | .278 | 1.12 | 7.4 | 2.7 | 6.8 | 80.2 | 66 | 29 | 25 | 7 | 24 | 60 | 0 | 1 | 2 | 0 | 0 | 3 | 1 | 3.65 |
| SP | Maddux, G.Maddux, Greg >> | 34 | 2000 | R | 57 | 21 | 0 | 5 | 3 | 3.97 | .320 | 1.32 | 9.3 | 2.6 | 5.8 | 34.0 | 35 | 15 | 15 | 5 | 10 | 22 | 0 | 4 | 0 | 0 | 0 | 3 | 1 | 4.76 |
| SP | Hamels, C.Hamels, Cole # >> | 25 | 2008 | L | 72 | 31 | 31 | 11 | 9 | 4.30 | .309 | 1.33 | 9.1 | 2.9 | 7.7 | 188.1 | 190 | 95 | 90 | 22 | 60 | 160 | 0 | 0 | 0 | 0 | 19 | 3 | 0 | 3.82 |