| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 27 | 27 | 9 | 10 | 3.41 | .263 | 1.06 | 7.0 | 2.6 | 9.1 | 182.0 | 141 | 76 | 69 | 21 | 52 | 185 | 2 | 0 | 0 | 1 | 18 | 2 | 0 | 3.36 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 87 | 26 | 26 | 12 | 9 | 4.14 | .310 | 1.31 | 7.9 | 3.9 | 8.3 | 178.1 | 156 | 89 | 82 | 23 | 78 | 165 | 3 | 0 | 0 | 1 | 13 | 6 | 4 | 4.24 |
| SP | Nola, A.Nola, Aaron † # >> | 25 | 2018 | R | 79 | 26 | 26 | 13 | 6 | 4.16 | .288 | 1.21 | 7.9 | 3.0 | 9.3 | 166.2 | 145 | 79 | 77 | 29 | 56 | 172 | 0 | 0 | 0 | 0 | 18 | 1 | 2 | 4.23 |
| SP | Liriano, F.Liriano, Francisco # >> | 23 | 2006 | L | 74 | 26 | 26 | 4 | 6 | 5.23 | .345 | 1.52 | 9.9 | 3.8 | 9.7 | 108.1 | 119 | 63 | 63 | 13 | 46 | 116 | 0 | 0 | 0 | 0 | 1 | 6 | 5 | 3.86 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 79 | 0 | 9 | 2 | 3.48 | .274 | 1.10 | 6.1 | 3.8 | 9.1 | 106.0 | 72 | 43 | 41 | 9 | 45 | 107 | 0 | 5 | 2 | 0 | 0 | 3 | 0 | 3.44 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 69 | 0 | 2 | 7 | 4.12 | .289 | 1.20 | 6.6 | 4.2 | 9.4 | 83.0 | 61 | 38 | 38 | 14 | 39 | 87 | 0 | 14 | 6 | 0 | 0 | 1 | 0 | 4.54 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 80 | 54 | 0 | 8 | 3 | 3.92 | .283 | 1.17 | 7.4 | 3.3 | 8.9 | 66.2 | 54 | 29 | 29 | 8 | 24 | 65 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 3.74 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 78 | 40 | 0 | 3 | 2 | 3.71 | .266 | 1.05 | 6.3 | 3.2 | 11.0 | 53.1 | 37 | 22 | 22 | 10 | 19 | 65 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 4.19 |