| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 27 | 27 | 15 | 8 | 3.34 | .266 | 1.08 | 7.1 | 2.6 | 9.5 | 202.1 | 159 | 77 | 75 | 21 | 59 | 213 | 7 | 0 | 0 | 3 | 19 | 2 | 7 | 3.15 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 26 | 26 | 7 | 13 | 4.83 | .310 | 1.33 | 8.9 | 3.1 | 9.3 | 169.2 | 167 | 93 | 91 | 23 | 58 | 174 | 0 | 0 | 0 | 0 | 13 | 4 | 5 | 3.81 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 81 | 25 | 25 | 10 | 10 | 3.73 | .268 | 1.05 | 7.1 | 2.4 | 6.8 | 178.1 | 140 | 75 | 74 | 17 | 47 | 134 | 7 | 0 | 0 | 0 | 15 | 9 | 4 | 3.68 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 75 | 25 | 25 | 10 | 9 | 5.05 | .324 | 1.41 | 9.3 | 3.3 | 7.2 | 155.0 | 161 | 87 | 87 | 25 | 57 | 124 | 1 | 0 | 0 | 0 | 12 | 5 | 3 | 4.70 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 49 | 0 | 3 | 3 | 2.81 | .263 | 1.05 | 6.4 | 3.2 | 10.6 | 51.1 | 36 | 16 | 16 | 7 | 18 | 60 | 0 | 28 | 5 | 0 | 0 | 1 | 0 | 3.55 |
| SU | Chapman, A.Chapman, Aroldis >> | 24 | 2012 | L | 87 | 45 | 0 | 2 | 2 | 2.81 | .242 | 0.92 | 4.9 | 3.4 | 9.9 | 48.0 | 26 | 15 | 15 | 4 | 18 | 53 | 0 | 5 | 3 | 0 | 0 | 2 | 0 | 3.13 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 66 | 31 | 0 | 2 | 0 | 3.03 | .252 | 1.01 | 6.4 | 2.8 | 8.5 | 35.2 | 25 | 12 | 12 | 3 | 11 | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.17 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 64 | 16 | 2 | 5 | 4 | 3.02 | .268 | 1.07 | 7.3 | 2.5 | 7.1 | 62.2 | 50 | 21 | 21 | 5 | 17 | 49 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 3.39 |