| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 26 | 26 | 12 | 6 | 3.38 | .281 | 1.14 | 7.9 | 2.4 | 10.4 | 175.2 | 153 | 69 | 66 | 23 | 47 | 202 | 2 | 0 | 0 | 1 | 16 | 6 | 7 | 3.31 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 26 | 26 | 7 | 11 | 5.77 | .325 | 1.43 | 10.0 | 2.9 | 9.5 | 128.0 | 142 | 82 | 82 | 25 | 41 | 135 | 0 | 0 | 0 | 0 | 10 | 2 | 5 | 4.44 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 78 | 25 | 25 | 11 | 7 | 4.45 | .336 | 1.49 | 9.6 | 3.9 | 6.9 | 143.2 | 152 | 83 | 71 | 21 | 62 | 109 | 0 | 0 | 0 | 0 | 11 | 4 | 2 | 4.77 |
| SP | Hendricks, K.Hendricks, Kyle # >> | 26 | 2016 | R | 73 | 25 | 25 | 10 | 9 | 3.92 | .280 | 1.16 | 7.7 | 2.7 | 5.7 | 151.2 | 130 | 71 | 66 | 18 | 46 | 96 | 3 | 0 | 0 | 2 | 14 | 1 | 3 | 4.21 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 94 | 70 | 0 | 2 | 3 | 4.41 | .282 | 1.14 | 6.6 | 3.8 | 10.8 | 85.2 | 62 | 42 | 42 | 16 | 36 | 102 | 0 | 1 | 2 | 0 | 0 | 3 | 0 | 4.42 |
| CL | Saito, T.Saito, Takashi † >> | 37 | 2007 | R | 90 | 51 | 0 | 7 | 6 | 4.44 | .324 | 1.42 | 9.0 | 4.0 | 8.3 | 50.2 | 50 | 28 | 25 | 8 | 22 | 46 | 0 | 28 | 6 | 0 | 0 | 1 | 0 | 4.62 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 88 | 53 | 0 | 1 | 4 | 2.82 | .257 | 1.04 | 5.7 | 3.8 | 11.4 | 60.2 | 38 | 20 | 19 | 8 | 25 | 76 | 0 | 1 | 3 | 0 | 0 | 0 | 2 | 3.45 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 86 | 47 | 0 | 4 | 2 | 4.47 | .274 | 1.10 | 8.1 | 1.9 | 9.8 | 58.1 | 52 | 29 | 29 | 8 | 12 | 63 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 3.34 |
| RP | Jackson, M.Jackson, Mike >> | 30 | 1994 | R | 82 | 35 | 0 | 3 | 2 | 4.26 | .301 | 1.29 | 8.7 | 3.2 | 10.2 | 31.2 | 30 | 18 | 15 | 8 | 11 | 35 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.16 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 74 | 19 | 0 | 1 | 0 | 3.32 | .305 | 1.32 | 8.5 | 3.3 | 9.9 | 19.0 | 18 | 7 | 7 | 2 | 7 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.26 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 71 | 24 | 0 | 1 | 0 | 4.11 | .313 | 1.30 | 8.7 | 3.3 | 13.2 | 30.2 | 29 | 14 | 14 | 6 | 11 | 44 | 0 | 0 | 1 | 0 | 0 | 2 | 2 | 3.97 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 21 | 1981 | L | 60 | 13 | 0 | 1 | 0 | 5.73 | .330 | 1.44 | 9.3 | 3.8 | 9.2 | 59.2 | 61 | 45 | 38 | 11 | 25 | 60 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 4.76 |