| SP | Harden, R.Harden, Rich $ >> | 27 | 2008 | R | 95 | 26 | 26 | 12 | 4 | 2.15 | .262 | 1.04 | 6.2 | 3.2 | 8.8 | 163.1 | 112 | 49 | 39 | 11 | 58 | 160 | 1 | 0 | 0 | 1 | 19 | 4 | 2 | 3.06 |
| SP | Perez, O.Perez, Oliver >> | 23 | 2004 | L | 76 | 25 | 25 | 12 | 8 | 4.10 | .315 | 1.35 | 8.1 | 4.1 | 9.3 | 151.1 | 136 | 76 | 69 | 18 | 69 | 156 | 0 | 0 | 0 | 0 | 14 | 4 | 3 | 3.93 |
| SP | Greinke, Z.Greinke, Zack † >> | 26 | 2009 | R | 77 | 25 | 25 | 18 | 2 | 3.45 | .298 | 1.22 | 8.5 | 2.5 | 8.1 | 154.0 | 145 | 60 | 59 | 11 | 43 | 138 | 1 | 0 | 0 | 1 | 16 | 8 | 5 | 3.13 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 56 | 0 | 8 | 1 | 2.79 | .290 | 1.20 | 7.3 | 3.6 | 9.4 | 67.2 | 54 | 22 | 21 | 4 | 27 | 70 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 2.99 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 70 | 46 | 0 | 3 | 2 | 3.48 | .326 | 1.44 | 8.3 | 4.7 | 9.5 | 54.1 | 50 | 24 | 21 | 2 | 28 | 57 | 0 | 2 | 1 | 0 | 0 | 1 | 3 | 2.98 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 80 | 39 | 0 | 1 | 1 | 1.61 | .295 | 1.19 | 4.7 | 6.1 | 9.8 | 44.2 | 23 | 8 | 8 | 3 | 30 | 48 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 3.95 |
| SU | Wagner, B.Wagner, Billy >> | 32 | 2003 | L | 90 | 50 | 0 | 2 | 3 | 2.98 | .279 | 1.12 | 7.2 | 3.0 | 9.5 | 54.1 | 43 | 18 | 18 | 6 | 18 | 57 | 0 | 3 | 5 | 0 | 0 | 2 | 2 | 3.44 |
| CL | Gagne, E.Gagne, Eric † # >> | 27 | 2003 | R | 100 | 55 | 0 | 2 | 4 | 3.79 | .258 | 1.01 | 5.3 | 3.8 | 10.4 | 59.1 | 35 | 26 | 25 | 7 | 25 | 68 | 0 | 32 | 3 | 0 | 0 | 2 | 2 | 3.61 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 48 | 10 | 0 | 3 | 1 | 4.61 | .339 | 1.54 | 11.1 | 3.5 | 10.4 | 13.2 | 16 | 7 | 7 | 2 | 5 | 15 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.85 |