| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 98 | 29 | 29 | 7 | 14 | 3.68 | .305 | 1.28 | 8.1 | 3.5 | 10.6 | 173.2 | 156 | 74 | 71 | 21 | 67 | 203 | 0 | 0 | 0 | 0 | 16 | 6 | 2 | 3.50 |
| SP | Gausman, K.Gausman, Kevin >> | 34 | 2025 | R | 81 | 28 | 28 | 10 | 9 | 4.13 | .319 | 1.34 | 8.6 | 3.5 | 8.7 | 172.0 | 165 | 81 | 79 | 15 | 66 | 167 | 1 | 0 | 0 | 1 | 14 | 11 | 2 | 3.53 |
| SP | Nelson, R.Nelson, Ryne >> | 27 | 2025 | R | 78 | 28 | 28 | 10 | 10 | 4.33 | .322 | 1.38 | 9.5 | 3.0 | 8.0 | 137.1 | 144 | 69 | 66 | 21 | 46 | 122 | 0 | 0 | 0 | 0 | 4 | 6 | 2 | 4.35 |
| SP | Kelly, M.Kelly, Merrill >> | 36 | 2025 | R | 68 | 28 | 28 | 11 | 8 | 4.08 | .332 | 1.47 | 9.8 | 3.5 | 8.2 | 163.1 | 177 | 81 | 74 | 23 | 63 | 148 | 0 | 0 | 0 | 0 | 14 | 4 | 2 | 4.25 |
| SP | Suarez, R.Suarez, Ranger >> | 29 | 2025 | L | 50 | 27 | 27 | 9 | 9 | 5.39 | .346 | 1.57 | 11.2 | 2.9 | 8.5 | 153.2 | 191 | 98 | 92 | 24 | 50 | 145 | 0 | 0 | 0 | 0 | 11 | 3 | 0 | 4.18 |
| CL | Hader, J.Hader, Josh † >> | 31 | 2025 | L | 100 | 67 | 0 | 2 | 6 | 2.60 | .254 | 1.01 | 5.5 | 3.6 | 11.5 | 65.2 | 40 | 19 | 19 | 6 | 26 | 83 | 0 | 33 | 1 | 0 | 0 | 1 | 2 | 2.89 |
| RP | Santana, D.Santana, Dennis >> | 29 | 2025 | R | 91 | 90 | 0 | 2 | 4 | 5.26 | .340 | 1.53 | 9.3 | 4.5 | 7.7 | 92.1 | 95 | 54 | 54 | 14 | 46 | 79 | 0 | 0 | 4 | 0 | 0 | 2 | 0 | 4.83 |
| RP | Kittredge, A.Kittredge, Andrew >> | 35 | 2025 | R | 83 | 72 | 0 | 6 | 2 | 2.99 | .280 | 1.13 | 7.3 | 2.9 | 11.6 | 75.1 | 61 | 26 | 25 | 9 | 24 | 97 | 0 | 4 | 1 | 0 | 0 | 3 | 3 | 3.05 |
| RP | Banks, T.Banks, Tanner † >> | 33 | 2025 | L | 68 | 90 | 0 | 11 | 0 | 4.63 | .304 | 1.30 | 9.0 | 2.8 | 8.0 | 81.2 | 81 | 44 | 42 | 8 | 25 | 72 | 0 | 2 | 4 | 0 | 0 | 1 | 2 | 3.47 |
| RP | Rogers, T.Rogers, Tyler >> | 34 | 2025 | R | 66 | 59 | 0 | 1 | 5 | 4.88 | .328 | 1.43 | 10.0 | 2.9 | 7.5 | 55.1 | 61 | 32 | 30 | 6 | 18 | 46 | 0 | 1 | 3 | 0 | 0 | 2 | 0 | 3.84 |