| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 96 | 36 | 36 | 14 | 16 | 3.22 | .277 | 1.13 | 7.8 | 2.3 | 4.9 | 279.2 | 243 | 117 | 100 | 26 | 72 | 152 | 12 | 0 | 0 | 1 | 25 | 6 | 5 | 3.96 |
| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 100 | 36 | 36 | 13 | 12 | 3.18 | .264 | 1.05 | 7.4 | 2.1 | 8.4 | 254.1 | 208 | 94 | 90 | 25 | 59 | 238 | 2 | 0 | 0 | 1 | 20 | 6 | 2 | 3.17 |
| SP | deGrom, J.deGrom, Jacob >> | 30 | 2018 | R | 96 | 33 | 33 | 14 | 14 | 3.60 | .280 | 1.16 | 7.8 | 2.6 | 8.0 | 240.1 | 208 | 104 | 96 | 22 | 70 | 214 | 2 | 0 | 0 | 1 | 19 | 3 | 3 | 3.32 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 94 | 49 | 0 | 5 | 4 | 2.14 | .298 | 1.23 | 8.0 | 3.1 | 9.6 | 46.1 | 41 | 16 | 11 | 4 | 16 | 49 | 0 | 3 | 4 | 0 | 0 | 2 | 1 | 3.17 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 89 | 28 | 0 | 6 | 2 | 2.74 | .242 | 0.96 | 7.0 | 1.6 | 7.8 | 23.0 | 18 | 7 | 7 | 3 | 4 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.48 |
| RP | Osuna, R.Osuna, Roberto >> | 22 | 2017 | R | 81 | 13 | 0 | 1 | 0 | 3.46 | .250 | 1.00 | 7.6 | 1.4 | 13.2 | 13.0 | 11 | 5 | 5 | 3 | 2 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.54 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 39 | 0 | 0 | 1 | 3.03 | .272 | 1.12 | 6.2 | 4.1 | 7.2 | 35.2 | 24 | 12 | 12 | 3 | 16 | 28 | 0 | 33 | 4 | 0 | 0 | 0 | 0 | 3.89 |
| SP | Radbourn, C.Radbourn, Charley # >> | 30 | 1884 | R | 86 | 12 | 5 | 1 | 3 | 6.37 | .348 | 1.58 | 11.7 | 2.6 | 4.0 | 59.1 | 77 | 44 | 42 | 12 | 17 | 26 | 0 | 0 | 0 | 0 | 1 | 1 | 3 | 5.68 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 84 | 5 | 1 | 2 | 0 | 3.47 | .286 | 1.16 | 7.4 | 3.1 | 4.7 | 23.1 | 19 | 9 | 9 | 4 | 8 | 12 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.39 |