| SP | Vazquez, J.Vazquez, Javier # >> | 33 | 2009 | R | 86 | 18 | 18 | 10 | 3 | 3.83 | .295 | 1.23 | 8.4 | 2.7 | 9.7 | 129.1 | 121 | 57 | 55 | 19 | 38 | 139 | 3 | 0 | 0 | 1 | 10 | 3 | 1 | 3.71 |
| SP | Williams, W.Williams, Woody >> | 36 | 2002 | R | 79 | 17 | 17 | 4 | 9 | 4.92 | .355 | 1.58 | 10.9 | 3.3 | 4.7 | 108.0 | 131 | 62 | 59 | 12 | 40 | 56 | 0 | 0 | 0 | 0 | 7 | 7 | 3 | 4.71 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 72 | 17 | 17 | 7 | 8 | 4.39 | .323 | 1.41 | 9.7 | 3.1 | 6.3 | 106.2 | 114 | 59 | 52 | 24 | 36 | 74 | 0 | 0 | 0 | 0 | 9 | 3 | 0 | 5.65 |
| RP | Papelbon, J.Papelbon, Jonathan † >> | 26 | 2006 | R | 93 | 50 | 0 | 6 | 0 | 2.75 | .248 | 0.98 | 5.3 | 3.6 | 9.8 | 68.2 | 40 | 22 | 21 | 8 | 27 | 74 | 0 | 6 | 2 | 0 | 0 | 1 | 4 | 3.59 |
| RP | Wagner, B.Wagner, Billy >> | 32 | 2003 | L | 90 | 39 | 0 | 2 | 3 | 3.45 | .225 | 0.85 | 4.4 | 3.3 | 8.6 | 47.0 | 23 | 18 | 18 | 6 | 17 | 45 | 0 | 8 | 2 | 0 | 0 | 1 | 2 | 3.89 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 83 | 25 | 0 | 3 | 0 | 0.51 | .205 | 0.74 | 4.9 | 1.8 | 7.2 | 35.0 | 19 | 2 | 2 | 1 | 7 | 28 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 2.46 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 78 | 13 | 0 | 1 | 3 | 7.82 | .397 | 1.97 | 12.8 | 6.0 | 8.3 | 12.2 | 17 | 11 | 11 | 4 | 8 | 11 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7.50 |
| RP | Okajima, H.Okajima, Hideki >> | 32 | 2007 | L | 53 | 8 | 0 | 1 | 0 | 1.17 | .258 | 1.04 | 2.6 | 7.7 | 9.0 | 7.2 | 2 | 1 | 1 | 0 | 6 | 7 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.57 |
| RP | Urbina, U.Urbina, Ugueth >> | 28 | 2002 | R | 44 | 11 | 0 | 0 | 0 | 5.40 | .298 | 1.28 | 6.2 | 5.5 | 9.7 | 13.1 | 9 | 8 | 8 | 3 | 8 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.69 |