| SP | Lincecum, T.Lincecum, Tim # >> | 25 | 2009 | R | 92 | 28 | 28 | 13 | 13 | 4.55 | .322 | 1.38 | 9.2 | 3.2 | 10.2 | 197.2 | 202 | 101 | 100 | 28 | 70 | 223 | 2 | 0 | 0 | 0 | 15 | 10 | 11 | 3.80 |
| SP | Bedard, E.Bedard, Erik # >> | 28 | 2007 | L | 80 | 27 | 27 | 8 | 9 | 4.89 | .347 | 1.54 | 10.5 | 3.4 | 9.8 | 165.2 | 192 | 97 | 90 | 25 | 63 | 180 | 1 | 0 | 0 | 1 | 14 | 9 | 1 | 4.10 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 50 | 27 | 27 | 9 | 8 | 5.80 | .339 | 1.51 | 9.8 | 3.9 | 7.2 | 170.2 | 185 | 114 | 110 | 34 | 73 | 136 | 1 | 0 | 0 | 0 | 10 | 4 | 4 | 5.36 |
| RP | Papelbon, J.Papelbon, Jonathan † >> | 26 | 2006 | R | 93 | 71 | 0 | 5 | 4 | 3.44 | .285 | 1.19 | 7.0 | 3.7 | 10.1 | 102.0 | 79 | 40 | 39 | 16 | 42 | 115 | 0 | 4 | 3 | 0 | 0 | 1 | 2 | 4.05 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 87 | 68 | 0 | 4 | 3 | 3.13 | .280 | 1.10 | 8.1 | 1.8 | 10.0 | 83.1 | 75 | 31 | 29 | 9 | 17 | 92 | 0 | 10 | 3 | 0 | 0 | 5 | 0 | 2.99 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 85 | 60 | 0 | 5 | 2 | 3.95 | .288 | 1.15 | 7.0 | 3.4 | 8.5 | 66.0 | 51 | 29 | 29 | 10 | 25 | 62 | 0 | 7 | 1 | 0 | 0 | 4 | 4 | 4.41 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 28 | 0 | 4 | 1 | 2.70 | .296 | 1.20 | 9.5 | 1.4 | 10.4 | 33.1 | 35 | 10 | 10 | 3 | 5 | 38 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 2.52 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 69 | 23 | 0 | 3 | 0 | 5.33 | .289 | 1.22 | 8.0 | 3.0 | 9.3 | 27.0 | 24 | 17 | 16 | 6 | 9 | 28 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.81 |
| RP | Guerrier, M.Guerrier, Matt >> | 31 | 2009 | R | 42 | 32 | 0 | 2 | 1 | 3.93 | .325 | 1.39 | 10.3 | 2.5 | 6.8 | 36.2 | 41 | 17 | 16 | 7 | 10 | 27 | 0 | 0 | 1 | 0 | 0 | 2 | 3 | 5.03 |