| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 33 | 33 | 14 | 9 | 3.98 | .293 | 1.20 | 8.8 | 2.0 | 10.4 | 240.0 | 235 | 112 | 106 | 37 | 53 | 278 | 6 | 0 | 0 | 2 | 18 | 11 | 2 | 3.49 |
| SP | Carpenter, C.Carpenter, Chris >> | 34 | 2009 | R | 79 | 33 | 33 | 12 | 14 | 5.50 | .347 | 1.54 | 10.9 | 3.0 | 6.2 | 209.1 | 254 | 135 | 128 | 25 | 69 | 145 | 3 | 0 | 0 | 2 | 14 | 10 | 5 | 4.30 |
| SP | Buehrle, M.Buehrle, Mark # >> | 22 | 2001 | L | 66 | 32 | 32 | 8 | 16 | 5.65 | .336 | 1.45 | 10.5 | 2.6 | 6.7 | 173.2 | 201 | 118 | 109 | 34 | 50 | 128 | 0 | 0 | 0 | 0 | 12 | 13 | 4 | 5.17 |
| SP | Clement, M.Clement, Matt >> | 28 | 2002 | R | 53 | 32 | 32 | 13 | 10 | 5.17 | .336 | 1.49 | 9.0 | 4.4 | 9.3 | 186.1 | 187 | 116 | 107 | 19 | 90 | 192 | 0 | 0 | 0 | 0 | 12 | 6 | 4 | 3.81 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 85 | 0 | 8 | 6 | 4.02 | .272 | 1.12 | 8.5 | 1.5 | 8.8 | 130.0 | 123 | 59 | 58 | 17 | 22 | 127 | 0 | 9 | 9 | 0 | 0 | 1 | 0 | 3.28 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 75 | 56 | 0 | 5 | 1 | 3.45 | .263 | 1.04 | 8.2 | 1.3 | 9.6 | 75.2 | 68 | 31 | 29 | 7 | 11 | 80 | 0 | 4 | 1 | 0 | 0 | 2 | 2 | 2.60 |
| RP | Perez, R.Perez, Rafael >> | 25 | 2007 | L | 64 | 52 | 0 | 4 | 2 | 2.94 | .255 | 0.99 | 6.0 | 3.0 | 9.3 | 64.1 | 43 | 21 | 21 | 8 | 21 | 66 | 0 | 8 | 1 | 0 | 0 | 2 | 2 | 3.64 |
| RP | Mota, G.Mota, Guillermo >> | 30 | 2003 | R | 49 | 41 | 0 | 0 | 2 | 2.77 | .257 | 1.00 | 6.2 | 2.8 | 7.1 | 52.0 | 36 | 16 | 16 | 10 | 16 | 41 | 0 | 6 | 1 | 0 | 0 | 2 | 0 | 4.96 |
| RP | Urbina, U.Urbina, Ugueth >> | 28 | 2002 | R | 42 | 34 | 0 | 3 | 0 | 3.66 | .293 | 1.24 | 8.0 | 3.3 | 8.2 | 46.2 | 41 | 20 | 19 | 8 | 17 | 42 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 4.54 |
| SP | Verlander, J.Verlander, Justin >> | 26 | 2009 | R | 43 | 9 | 0 | 1 | 2 | 14.40 | .492 | 2.90 | 21.6 | 4.5 | 9.9 | 10.0 | 24 | 16 | 16 | 4 | 5 | 11 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 7.50 |