| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 35 | 35 | 11 | 7 | 3.13 | .287 | 1.18 | 7.9 | 2.7 | 9.8 | 167.0 | 146 | 65 | 58 | 10 | 51 | 182 | 0 | 0 | 0 | 0 | 1 | 5 | 6 | 2.60 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 86 | 34 | 34 | 15 | 13 | 4.02 | .300 | 1.27 | 9.2 | 2.1 | 6.9 | 260.0 | 267 | 116 | 116 | 36 | 62 | 198 | 9 | 0 | 0 | 2 | 19 | 6 | 4 | 4.06 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 77 | 33 | 33 | 15 | 10 | 4.87 | .336 | 1.48 | 9.9 | 3.5 | 7.3 | 197.2 | 216 | 115 | 107 | 36 | 77 | 159 | 0 | 0 | 0 | 0 | 15 | 7 | 5 | 5.04 |
| SP | Greinke, Z.Greinke, Zack >> | 26 | 2009 | R | 76 | 33 | 33 | 14 | 9 | 4.47 | .320 | 1.37 | 9.6 | 2.8 | 8.1 | 209.1 | 222 | 115 | 104 | 31 | 65 | 189 | 1 | 0 | 0 | 1 | 15 | 9 | 4 | 4.18 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 85 | 98 | 0 | 9 | 9 | 3.85 | .297 | 1.25 | 6.4 | 4.9 | 9.2 | 126.1 | 89 | 56 | 54 | 10 | 69 | 129 | 0 | 4 | 1 | 0 | 0 | 2 | 6 | 3.67 |
| RP | Percival, T.Percival, Troy † >> | 38 | 2007 | R | 84 | 86 | 0 | 4 | 4 | 2.50 | .260 | 1.02 | 6.9 | 2.3 | 6.4 | 122.1 | 94 | 42 | 34 | 13 | 31 | 87 | 0 | 9 | 3 | 0 | 0 | 4 | 3 | 3.82 |
| RP | Wheeler, D.Wheeler, Dan >> | 32 | 2009 | R | 67 | 79 | 0 | 3 | 9 | 4.95 | .336 | 1.47 | 10.7 | 2.6 | 5.6 | 96.1 | 114 | 53 | 53 | 15 | 28 | 60 | 0 | 7 | 6 | 0 | 0 | 4 | 3 | 4.78 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 59 | 59 | 0 | 5 | 4 | 4.02 | .288 | 1.18 | 6.4 | 4.3 | 9.4 | 69.1 | 49 | 32 | 31 | 10 | 33 | 72 | 0 | 5 | 2 | 0 | 0 | 2 | 1 | 4.32 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 54 | 46 | 0 | 1 | 0 | 4.14 | .348 | 1.55 | 8.4 | 5.8 | 8.2 | 45.2 | 42 | 21 | 21 | 3 | 29 | 41 | 0 | 8 | 1 | 0 | 0 | 2 | 4 | 4.11 |