| SP | Johnson, R.Johnson, Randy >> | 38 | 2001 | L | 97 | 33 | 33 | 13 | 11 | 4.92 | .334 | 1.48 | 9.3 | 4.1 | 9.9 | 215.2 | 222 | 129 | 118 | 30 | 98 | 236 | 0 | 0 | 0 | 0 | 16 | 5 | 7 | 4.06 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 86 | 32 | 32 | 8 | 15 | 4.61 | .319 | 1.39 | 10.0 | 2.5 | 6.3 | 210.2 | 233 | 128 | 108 | 27 | 59 | 147 | 4 | 0 | 0 | 0 | 15 | 4 | 3 | 4.17 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 77 | 31 | 31 | 14 | 10 | 4.90 | .339 | 1.51 | 10.4 | 3.2 | 6.7 | 174.1 | 202 | 114 | 95 | 32 | 61 | 130 | 0 | 0 | 0 | 0 | 16 | 5 | 1 | 5.03 |
| SP | Maine, J.Maine, John # >> | 25 | 2006 | R | 69 | 31 | 31 | 13 | 10 | 5.51 | .325 | 1.44 | 9.2 | 3.8 | 7.6 | 168.1 | 171 | 118 | 103 | 35 | 71 | 141 | 0 | 0 | 0 | 0 | 11 | 1 | 4 | 5.32 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 87 | 84 | 0 | 8 | 2 | 3.09 | .309 | 1.32 | 7.8 | 4.1 | 8.4 | 102.0 | 88 | 44 | 35 | 16 | 47 | 95 | 0 | 1 | 2 | 0 | 0 | 2 | 3 | 4.62 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 79 | 74 | 0 | 8 | 5 | 3.86 | .305 | 1.26 | 6.3 | 5.1 | 9.4 | 88.2 | 62 | 40 | 38 | 9 | 50 | 92 | 0 | 2 | 4 | 0 | 0 | 5 | 1 | 4.11 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 62 | 0 | 6 | 2 | 2.79 | .278 | 1.10 | 7.7 | 2.2 | 9.4 | 71.0 | 61 | 26 | 22 | 3 | 17 | 74 | 0 | 0 | 0 | 0 | 0 | 4 | 6 | 2.35 |
| RP | Cormier, R.Cormier, Rheal >> | 36 | 2003 | L | 62 | 45 | 0 | 3 | 0 | 2.61 | .289 | 1.16 | 7.2 | 3.4 | 6.2 | 51.2 | 41 | 25 | 15 | 7 | 19 | 35 | 0 | 2 | 0 | 0 | 0 | 3 | 0 | 4.71 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 58 | 37 | 0 | 0 | 0 | 3.94 | .259 | 1.05 | 6.4 | 3.2 | 8.0 | 45.2 | 32 | 21 | 20 | 7 | 16 | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.31 |