| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 18 | 18 | 3 | 7 | 4.98 | .309 | 1.32 | 9.2 | 2.7 | 8.0 | 86.2 | 88 | 51 | 48 | 12 | 26 | 76 | 0 | 0 | 0 | 0 | 2 | 2 | 3 | 4.02 |
| SP | Duchscherer, J.Duchscherer, Justin † # >> | 31 | 2008 | R | 84 | 18 | 18 | 12 | 5 | 3.77 | .281 | 1.14 | 7.6 | 2.7 | 6.1 | 129.0 | 109 | 56 | 54 | 15 | 38 | 87 | 2 | 0 | 0 | 1 | 11 | 4 | 0 | 4.14 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 68 | 17 | 17 | 7 | 8 | 5.15 | .326 | 1.43 | 9.9 | 3.0 | 6.5 | 108.1 | 119 | 63 | 62 | 15 | 36 | 78 | 0 | 0 | 0 | 0 | 8 | 2 | 3 | 4.42 |
| SP | Millwood, K.Millwood, Kevin >> | 28 | 2002 | R | 52 | 17 | 17 | 5 | 9 | 5.87 | .349 | 1.59 | 10.5 | 3.8 | 5.8 | 99.2 | 116 | 67 | 65 | 20 | 42 | 64 | 0 | 0 | 0 | 0 | 9 | 2 | 3 | 5.67 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 86 | 46 | 0 | 2 | 4 | 3.77 | .317 | 1.36 | 6.3 | 6.0 | 8.8 | 57.1 | 40 | 24 | 24 | 7 | 38 | 56 | 0 | 3 | 0 | 0 | 0 | 2 | 3 | 4.74 |
| RP | Williamson, S.Williamson, Scott >> | 26 | 2002 | R | 52 | 26 | 0 | 0 | 1 | 4.65 | .311 | 1.35 | 6.4 | 5.8 | 10.2 | 31.0 | 22 | 16 | 16 | 3 | 20 | 35 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 3.94 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 32 | 2004 | R | 41 | 22 | 0 | 1 | 1 | 4.81 | .284 | 1.19 | 7.1 | 3.8 | 6.8 | 24.1 | 19 | 15 | 13 | 4 | 10 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.92 |