| SP | Santana, J.Santana, Johan † >> | 25 | 2004 | L | 100 | 19 | 19 | 10 | 5 | 2.69 | .266 | 1.07 | 7.6 | 2.1 | 9.5 | 140.2 | 118 | 45 | 42 | 10 | 32 | 147 | 3 | 0 | 0 | 3 | 14 | 3 | 6 | 2.58 |
| SP | Vazquez, J.Vazquez, Javier † # >> | 33 | 2009 | R | 88 | 18 | 18 | 10 | 2 | 3.80 | .267 | 1.08 | 7.9 | 1.8 | 9.3 | 137.1 | 121 | 59 | 58 | 19 | 28 | 141 | 3 | 0 | 0 | 2 | 9 | 1 | 2 | 3.38 |
| SP | Wakefield, T.Wakefield, Tim >> | 36 | 2002 | R | 84 | 18 | 18 | 1 | 4 | 3.47 | .301 | 1.25 | 7.4 | 4.0 | 7.5 | 72.2 | 59 | 32 | 28 | 11 | 32 | 60 | 0 | 0 | 0 | 0 | 0 | 3 | 5 | 4.78 |
| SP | Bedard, E.Bedard, Erik >> | 28 | 2007 | L | 79 | 17 | 17 | 4 | 9 | 5.20 | .341 | 1.51 | 9.3 | 4.3 | 10.3 | 109.0 | 113 | 65 | 63 | 17 | 52 | 125 | 1 | 0 | 0 | 0 | 7 | 4 | 0 | 4.28 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 67 | 17 | 17 | 7 | 7 | 6.14 | .339 | 1.51 | 10.5 | 3.1 | 6.6 | 110.0 | 128 | 75 | 75 | 21 | 38 | 81 | 1 | 0 | 0 | 0 | 6 | 3 | 1 | 5.13 |
| RP | Soriano, R.Soriano, Rafael † >> | 24 | 2003 | R | 97 | 50 | 0 | 5 | 2 | 2.87 | .274 | 1.07 | 6.3 | 3.4 | 8.7 | 69.0 | 48 | 25 | 22 | 8 | 26 | 67 | 0 | 7 | 2 | 0 | 0 | 4 | 0 | 3.87 |
| RP | Wagner, B.Wagner, Billy >> | 32 | 2003 | L | 89 | 38 | 0 | 3 | 3 | 4.11 | .317 | 1.37 | 8.2 | 4.1 | 10.6 | 46.0 | 42 | 22 | 21 | 6 | 21 | 54 | 0 | 4 | 5 | 0 | 0 | 1 | 2 | 3.78 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 85 | 33 | 0 | 1 | 5 | 3.98 | .299 | 1.26 | 6.5 | 4.8 | 8.6 | 43.0 | 31 | 24 | 19 | 6 | 23 | 41 | 0 | 3 | 3 | 0 | 0 | 1 | 2 | 4.58 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 66 | 27 | 0 | 3 | 3 | 5.60 | .349 | 1.61 | 8.7 | 6.0 | 7.0 | 27.1 | 26 | 17 | 17 | 4 | 18 | 21 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 5.37 |