| SP | Hernandez, F.Hernandez, Felix † # >> | 19 | 2005 | R | 96 | 19 | 19 | 14 | 5 | 3.74 | .285 | 1.17 | 7.8 | 2.7 | 6.9 | 139.2 | 121 | 60 | 58 | 21 | 42 | 106 | 3 | 0 | 0 | 2 | 11 | 4 | 5 | 4.43 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 68 | 18 | 18 | 4 | 5 | 6.20 | .368 | 1.71 | 11.4 | 3.9 | 6.7 | 103.0 | 131 | 75 | 71 | 20 | 45 | 77 | 0 | 0 | 0 | 0 | 5 | 4 | 1 | 5.46 |
| SP | Shields, J.Shields, James >> | 26 | 2007 | R | 54 | 17 | 17 | 4 | 6 | 5.64 | .346 | 1.57 | 10.9 | 3.2 | 7.0 | 107.0 | 130 | 72 | 67 | 22 | 38 | 83 | 0 | 0 | 0 | 0 | 6 | 2 | 10 | 5.24 |
| SP | Willis, D.Willis, Dontrelle >> | 23 | 2005 | L | 49 | 17 | 17 | 5 | 7 | 5.47 | .334 | 1.47 | 9.6 | 3.6 | 7.1 | 100.1 | 107 | 64 | 61 | 16 | 40 | 79 | 0 | 0 | 0 | 0 | 7 | 4 | 2 | 4.82 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 50 | 0 | 2 | 3 | 3.82 | .310 | 1.30 | 9.1 | 2.6 | 8.2 | 68.1 | 69 | 29 | 29 | 8 | 20 | 62 | 0 | 7 | 1 | 0 | 0 | 3 | 0 | 3.72 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 55 | 34 | 0 | 5 | 1 | 6.87 | .349 | 1.61 | 10.0 | 4.8 | 10.5 | 36.2 | 40 | 28 | 28 | 10 | 19 | 42 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 5.86 |
| RP | Urbina, U.Urbina, Ugueth >> | 28 | 2002 | R | 45 | 30 | 0 | 0 | 1 | 3.90 | .297 | 1.27 | 7.9 | 3.7 | 10.1 | 32.1 | 28 | 14 | 14 | 7 | 13 | 36 | 0 | 8 | 0 | 0 | 0 | 0 | 1 | 4.81 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 34 | 23 | 0 | 1 | 1 | 4.26 | .307 | 1.33 | 7.5 | 4.6 | 9.3 | 31.2 | 26 | 15 | 15 | 3 | 16 | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.74 |