| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 12 | 12 | 4 | 3 | 3.56 | .290 | 1.16 | 6.8 | 3.7 | 5.9 | 78.1 | 59 | 32 | 31 | 12 | 32 | 51 | 1 | 0 | 0 | 1 | 7 | 5 | 0 | 5.12 |
| SP | Alvarez, W.Alvarez, Wilson >> | 33 | 2003 | L | 73 | 12 | 12 | 3 | 1 | 5.19 | .307 | 1.31 | 8.5 | 3.4 | 6.8 | 50.1 | 47 | 29 | 29 | 7 | 19 | 38 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 4.50 |
| SP | Zambrano, C.Zambrano, Carlos # >> | 24 | 2005 | R | 70 | 12 | 12 | 0 | 4 | 5.73 | .329 | 1.45 | 8.0 | 5.0 | 6.5 | 66.0 | 59 | 46 | 42 | 12 | 37 | 48 | 0 | 0 | 0 | 0 | 5 | 1 | 2 | 5.64 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 60 | 12 | 12 | 6 | 1 | 5.29 | .374 | 1.71 | 10.5 | 4.9 | 7.3 | 68.0 | 79 | 43 | 40 | 16 | 37 | 55 | 0 | 0 | 0 | 0 | 6 | 6 | 3 | 6.34 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 100 | 36 | 0 | 1 | 1 | 2.60 | .228 | 0.87 | 5.5 | 2.3 | 9.9 | 52.0 | 32 | 16 | 15 | 4 | 13 | 57 | 0 | 4 | 3 | 0 | 0 | 1 | 0 | 2.62 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 79 | 35 | 0 | 3 | 5 | 3.83 | .298 | 1.25 | 6.5 | 4.9 | 9.6 | 44.2 | 32 | 21 | 19 | 6 | 24 | 47 | 0 | 1 | 4 | 0 | 0 | 1 | 2 | 4.34 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 67 | 31 | 0 | 4 | 4 | 4.91 | .333 | 1.42 | 8.8 | 4.3 | 11.3 | 36.2 | 35 | 20 | 20 | 6 | 17 | 45 | 0 | 3 | 1 | 0 | 0 | 3 | 0 | 4.33 |
| RP | Wheeler, D.Wheeler, Dan >> | 32 | 2009 | R | 67 | 26 | 0 | 5 | 2 | 3.21 | .289 | 1.22 | 7.1 | 4.1 | 8.2 | 33.2 | 26 | 14 | 12 | 4 | 15 | 30 | 0 | 1 | 3 | 0 | 0 | 0 | 1 | 4.12 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 60 | 19 | 0 | 2 | 1 | 4.30 | .296 | 1.22 | 6.3 | 4.7 | 8.6 | 23.0 | 16 | 11 | 11 | 3 | 12 | 22 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 4.48 |
| RP | Kim, B.Kim, Byung-Hyun >> | 22 | 2001 | R | 58 | 17 | 0 | 1 | 1 | 2.45 | .290 | 1.23 | 5.3 | 5.7 | 10.2 | 22.0 | 13 | 6 | 6 | 0 | 14 | 25 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 2.64 |