| SP | Johnson, R.Johnson, Randy >> | 38 | 2001 | L | 97 | 18 | 18 | 6 | 6 | 3.56 | .278 | 1.13 | 7.9 | 2.3 | 10.2 | 129.0 | 113 | 51 | 51 | 17 | 33 | 146 | 4 | 0 | 0 | 0 | 11 | 3 | 2 | 3.29 |
| SP | Duchscherer, J.Duchscherer, Justin >> | 31 | 2008 | R | 85 | 18 | 18 | 4 | 9 | 6.51 | .333 | 1.47 | 10.6 | 2.7 | 7.2 | 92.2 | 108 | 68 | 67 | 18 | 28 | 74 | 1 | 0 | 0 | 0 | 7 | 3 | 2 | 4.95 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 70 | 17 | 17 | 3 | 9 | 6.24 | .389 | 1.86 | 10.4 | 6.3 | 6.1 | 88.0 | 102 | 63 | 61 | 15 | 62 | 60 | 0 | 0 | 0 | 0 | 5 | 4 | 0 | 6.10 |
| SP | Shields, J.Shields, James >> | 26 | 2007 | R | 52 | 21 | 17 | 10 | 4 | 5.18 | .338 | 1.51 | 11.5 | 2.2 | 6.8 | 104.1 | 133 | 63 | 60 | 14 | 25 | 78 | 2 | 0 | 1 | 0 | 9 | 2 | 4 | 4.03 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 60 | 0 | 2 | 2 | 3.79 | .333 | 1.47 | 10.3 | 3.0 | 9.9 | 71.1 | 81 | 31 | 30 | 7 | 24 | 78 | 0 | 3 | 0 | 0 | 0 | 2 | 1 | 3.18 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 53 | 0 | 3 | 5 | 3.97 | .337 | 1.49 | 8.1 | 5.3 | 10.2 | 59.0 | 53 | 27 | 26 | 6 | 35 | 67 | 0 | 6 | 2 | 0 | 0 | 2 | 1 | 3.93 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 77 | 41 | 0 | 3 | 4 | 6.65 | .355 | 1.61 | 9.4 | 5.1 | 10.8 | 46.0 | 48 | 36 | 34 | 13 | 26 | 55 | 0 | 3 | 3 | 0 | 0 | 2 | 0 | 6.11 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 60 | 35 | 0 | 4 | 1 | 7.93 | .411 | 2.04 | 11.5 | 7.0 | 11.5 | 36.1 | 46 | 32 | 32 | 8 | 28 | 46 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 5.83 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 51 | 62 | 0 | 1 | 1 | 4.70 | .317 | 1.34 | 9.0 | 3.2 | 11.3 | 51.2 | 51 | 28 | 27 | 5 | 18 | 64 | 0 | 2 | 4 | 0 | 0 | 3 | 1 | 3.00 |