| SP | Imanaga, S.Imanaga, Shota # >> | 31 | 2025 | L | 80 | 27 | 24 | 12 | 4 | 3.45 | .291 | 1.19 | 8.3 | 2.5 | 6.7 | 156.2 | 144 | 61 | 60 | 17 | 43 | 116 | 1 | 0 | 0 | 1 | 13 | 6 | 0 | 3.87 |
| SP | Abbott, A.Abbott, Andrew # >> | 26 | 2025 | L | 65 | 18 | 11 | 6 | 6 | 3.80 | .321 | 1.36 | 9.0 | 3.4 | 7.0 | 94.2 | 94 | 45 | 40 | 10 | 35 | 73 | 0 | 0 | 0 | 0 | 5 | 5 | 0 | 4.11 |
| SP | Cameron, N.Cameron, Noah # >> | 25 | 2025 | L | 77 | 26 | 23 | 11 | 7 | 4.21 | .288 | 1.20 | 8.0 | 2.8 | 8.1 | 139.0 | 124 | 67 | 65 | 21 | 43 | 125 | 0 | 0 | 0 | 0 | 13 | 2 | 2 | 4.14 |
| SP | Gausman, K.Gausman, Kevin # >> | 34 | 2025 | R | 81 | 27 | 22 | 5 | 8 | 5.53 | .321 | 1.35 | 9.1 | 3.1 | 8.7 | 127.0 | 128 | 79 | 78 | 15 | 44 | 123 | 0 | 0 | 0 | 0 | 9 | 8 | 1 | 3.83 |
| RP | Rodríguez, R.Rodríguez, Randy # $ >> | 25 | 2025 | R | 95 | 61 | 0 | 3 | 3 | 4.43 | .300 | 1.25 | 7.8 | 3.5 | 9.4 | 67.0 | 58 | 35 | 33 | 5 | 26 | 70 | 0 | 1 | 1 | 0 | 0 | 2 | 5 | 3.13 |
| RP | Coulombe, D.Coulombe, Daniel >> | 35 | 2025 | L | 61 | 45 | 0 | 3 | 3 | 3.59 | .306 | 1.28 | 6.9 | 4.8 | 9.4 | 47.2 | 36 | 19 | 19 | 4 | 25 | 49 | 0 | 4 | 3 | 0 | 0 | 2 | 2 | 3.74 |
| RP | Stewart, B.Stewart, Brock >> | 33 | 2025 | R | 54 | 13 | 0 | 1 | 0 | 3.45 | .319 | 1.40 | 10.2 | 3.0 | 10.8 | 15.2 | 17 | 6 | 6 | 2 | 5 | 18 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.33 |
| RP | Gaddis, H.Gaddis, Hunter >> | 27 | 2025 | R | 53 | 16 | 0 | 0 | 3 | 7.82 | .406 | 2.05 | 13.5 | 6.0 | 5.3 | 12.2 | 18 | 11 | 11 | 3 | 8 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 7.08 |
| CL | Hader, J.Hader, Josh † >> | 31 | 2025 | L | 100 | 50 | 0 | 5 | 2 | 2.26 | .269 | 1.03 | 5.6 | 3.7 | 12.9 | 51.2 | 32 | 14 | 13 | 5 | 21 | 73 | 0 | 33 | 3 | 0 | 0 | 4 | 1 | 2.88 |
| SU | Svanson, M.Svanson, Matt >> | 26 | 2025 | R | 97 | 57 | 0 | 3 | 1 | 3.00 | .299 | 1.26 | 7.1 | 4.3 | 9.9 | 57.0 | 45 | 22 | 19 | 5 | 27 | 63 | 0 | 11 | 3 | 0 | 0 | 1 | 0 | 3.40 |