| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 20 | 20 | 8 | 5 | 3.44 | .266 | 1.07 | 7.2 | 2.4 | 9.4 | 133.1 | 107 | 56 | 51 | 13 | 35 | 139 | 1 | 0 | 0 | 0 | 15 | 3 | 0 | 3.04 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 94 | 19 | 19 | 3 | 5 | 2.27 | .238 | 0.92 | 5.7 | 2.5 | 8.8 | 99.0 | 63 | 29 | 25 | 10 | 28 | 97 | 0 | 0 | 0 | 0 | 5 | 2 | 1 | 3.26 |
| SP | Candelaria, J.Candelaria, John >> | 33 | 1986 | L | 90 | 18 | 18 | 6 | 4 | 5.08 | .317 | 1.36 | 8.8 | 3.5 | 7.0 | 95.2 | 93 | 55 | 54 | 11 | 37 | 74 | 0 | 0 | 0 | 0 | 3 | 3 | 1 | 4.21 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 88 | 19 | 16 | 7 | 5 | 5.16 | .330 | 1.44 | 10.4 | 2.5 | 8.8 | 103.0 | 119 | 61 | 59 | 24 | 29 | 101 | 0 | 0 | 0 | 0 | 7 | 4 | 1 | 5.03 |
| SP | Gonzalez, G.Gonzalez, Gio >> | 27 | 2012 | L | 86 | 16 | 12 | 5 | 4 | 5.66 | .328 | 1.42 | 7.6 | 5.3 | 8.2 | 82.2 | 69 | 55 | 52 | 12 | 48 | 75 | 0 | 1 | 0 | 0 | 7 | 4 | 2 | 4.98 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 48 | 0 | 8 | 4 | 2.76 | .266 | 1.09 | 6.6 | 3.3 | 11.5 | 71.2 | 52 | 23 | 22 | 6 | 26 | 91 | 0 | 2 | 4 | 0 | 0 | 0 | 4 | 2.63 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 96 | 47 | 0 | 1 | 5 | 4.40 | .323 | 1.40 | 7.4 | 5.2 | 9.6 | 57.1 | 47 | 28 | 28 | 8 | 33 | 61 | 0 | 8 | 3 | 0 | 0 | 2 | 3 | 4.53 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 96 | 38 | 0 | 4 | 2 | 1.33 | .232 | 0.89 | 5.7 | 2.3 | 10.7 | 47.1 | 30 | 8 | 7 | 2 | 12 | 56 | 0 | 4 | 0 | 0 | 0 | 1 | 1 | 2.00 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 94 | 32 | 0 | 2 | 3 | 3.73 | .319 | 1.37 | 7.5 | 4.9 | 9.6 | 31.1 | 26 | 13 | 13 | 3 | 17 | 33 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 3.87 |
| RP | Aguilera, R.Aguilera, Rick >> | 31 | 1992 | R | 64 | 22 | 0 | 0 | 2 | 2.86 | .227 | 0.88 | 5.1 | 2.9 | 6.4 | 28.1 | 16 | 9 | 9 | 4 | 9 | 20 | 0 | 3 | 1 | 0 | 0 | 0 | 3 | 4.39 |
| RP | Fuentes, B.Fuentes, Brian >> | 34 | 2009 | L | 44 | 17 | 0 | 1 | 1 | 1.77 | .299 | 1.23 | 7.2 | 4.1 | 7.7 | 20.1 | 16 | 4 | 4 | 0 | 9 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.80 |