| SP | Buchholz, C.Buchholz, Clay >> | 29 | 2013 | R | 81 | 31 | 31 | 10 | 15 | 5.13 | .337 | 1.49 | 9.1 | 4.3 | 6.9 | 203.2 | 205 | 125 | 116 | 23 | 98 | 156 | 3 | 0 | 0 | 1 | 12 | 8 | 2 | 4.50 |
| SP | Strasburg, S.Strasburg, Stephen >> | 30 | 2019 | R | 78 | 30 | 30 | 8 | 14 | 4.69 | .316 | 1.35 | 8.4 | 3.7 | 10.2 | 188.0 | 176 | 108 | 98 | 37 | 77 | 214 | 2 | 0 | 0 | 1 | 15 | 7 | 4 | 4.62 |
| SP | Iwakuma, H.Iwakuma, Hisashi # >> | 32 | 2013 | R | 64 | 30 | 30 | 13 | 9 | 4.56 | .298 | 1.25 | 8.6 | 2.6 | 7.7 | 205.1 | 197 | 108 | 104 | 32 | 59 | 175 | 4 | 0 | 0 | 0 | 15 | 6 | 6 | 4.27 |
| SP | Lackey, J.Lackey, John >> | 38 | 2016 | R | 60 | 30 | 30 | 7 | 14 | 5.99 | .349 | 1.59 | 9.6 | 4.8 | 7.3 | 183.1 | 195 | 129 | 122 | 38 | 97 | 148 | 0 | 0 | 0 | 0 | 12 | 3 | 2 | 5.72 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 98 | 79 | 0 | 2 | 7 | 4.34 | .300 | 1.26 | 8.4 | 3.0 | 9.7 | 105.2 | 98 | 56 | 51 | 18 | 35 | 113 | 0 | 8 | 7 | 0 | 0 | 3 | 1 | 4.16 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 81 | 75 | 0 | 7 | 5 | 3.88 | .333 | 1.47 | 8.2 | 5.1 | 9.7 | 92.2 | 84 | 44 | 40 | 12 | 52 | 99 | 0 | 7 | 4 | 0 | 0 | 3 | 3 | 4.34 |
| RP | McHugh, C.McHugh, Collin >> | 31 | 2018 | R | 64 | 62 | 0 | 7 | 7 | 3.69 | .286 | 1.19 | 7.0 | 3.7 | 10.1 | 68.1 | 53 | 30 | 28 | 10 | 28 | 76 | 0 | 7 | 3 | 0 | 0 | 1 | 0 | 3.96 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 34 | 2014 | R | 47 | 43 | 0 | 2 | 1 | 3.80 | .349 | 1.61 | 10.1 | 4.4 | 6.7 | 47.1 | 53 | 20 | 20 | 6 | 23 | 35 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 4.64 |
| RP | Smith, C.Smith, Carson >> | 25 | 2015 | R | 37 | 42 | 0 | 2 | 2 | 6.51 | .319 | 1.38 | 9.8 | 2.7 | 10.3 | 47.0 | 51 | 34 | 34 | 10 | 14 | 54 | 0 | 2 | 0 | 0 | 0 | 1 | 6 | 4.43 |
| SP | Paxton, J.Paxton, James >> | 29 | 2018 | L | 46 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |