| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 19 | 19 | 6 | 9 | 4.29 | .304 | 1.27 | 7.9 | 3.6 | 7.1 | 134.1 | 117 | 67 | 64 | 19 | 53 | 106 | 2 | 0 | 0 | 0 | 10 | 6 | 1 | 4.58 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 18 | 18 | 7 | 7 | 5.72 | .296 | 1.24 | 8.7 | 2.6 | 9.2 | 111.2 | 107 | 74 | 71 | 25 | 32 | 113 | 3 | 0 | 0 | 1 | 6 | 2 | 4 | 4.81 |
| SP | Mathewson, C.Mathewson, Christy † >> | 28 | 1908 | R | 82 | 17 | 17 | 11 | 3 | 2.86 | .262 | 1.05 | 6.9 | 2.5 | 4.1 | 126.0 | 97 | 45 | 40 | 11 | 35 | 57 | 2 | 0 | 0 | 0 | 12 | 2 | 2 | 4.11 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 17 | 17 | 6 | 6 | 7.12 | .380 | 1.81 | 11.7 | 4.6 | 4.5 | 97.1 | 126 | 77 | 77 | 22 | 50 | 48 | 0 | 0 | 0 | 0 | 4 | 3 | 4 | 6.60 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 17 | 17 | 5 | 10 | 5.58 | .326 | 1.40 | 9.8 | 2.8 | 7.8 | 109.2 | 119 | 72 | 68 | 20 | 34 | 95 | 4 | 0 | 0 | 1 | 5 | 6 | 2 | 4.74 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 42 | 0 | 2 | 2 | 1.21 | .230 | 0.90 | 5.3 | 2.9 | 10.0 | 44.2 | 26 | 7 | 6 | 2 | 14 | 49 | 0 | 25 | 1 | 0 | 0 | 0 | 0 | 2.32 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 43 | 0 | 4 | 3 | 4.64 | .302 | 1.28 | 8.1 | 3.5 | 7.6 | 52.1 | 47 | 27 | 27 | 12 | 20 | 44 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.52 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 32 | 0 | 0 | 2 | 5.40 | .306 | 1.30 | 7.0 | 4.7 | 6.5 | 40.0 | 31 | 27 | 24 | 11 | 21 | 29 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.78 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 27 | 0 | 0 | 0 | 3.34 | .340 | 1.48 | 8.4 | 5.1 | 11.5 | 32.1 | 30 | 12 | 12 | 3 | 18 | 41 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 3.53 |