| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 32 | 32 | 13 | 9 | 5.41 | .312 | 1.33 | 10.2 | 1.8 | 8.1 | 201.1 | 228 | 122 | 121 | 35 | 40 | 181 | 4 | 0 | 0 | 0 | 14 | 6 | 10 | 4.15 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 29 | 29 | 9 | 13 | 6.56 | .353 | 1.59 | 10.7 | 3.8 | 6.4 | 168.2 | 199 | 138 | 123 | 34 | 70 | 120 | 6 | 0 | 0 | 3 | 8 | 7 | 2 | 5.58 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 46 | 32 | 31 | 7 | 15 | 6.56 | .381 | 1.81 | 10.4 | 5.9 | 10.0 | 181.0 | 209 | 141 | 132 | 28 | 119 | 202 | 2 | 0 | 0 | 1 | 10 | 6 | 10 | 4.85 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 64 | 0 | 5 | 3 | 3.76 | .316 | 1.37 | 7.8 | 4.6 | 9.9 | 67.0 | 58 | 32 | 28 | 7 | 34 | 74 | 0 | 28 | 3 | 0 | 0 | 1 | 3 | 3.72 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 85 | 0 | 5 | 4 | 5.92 | .368 | 1.73 | 10.9 | 4.7 | 7.4 | 97.1 | 117 | 66 | 64 | 24 | 51 | 80 | 0 | 2 | 1 | 0 | 0 | 2 | 8 | 6.21 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 78 | 0 | 3 | 0 | 3.38 | .318 | 1.39 | 7.8 | 4.7 | 7.9 | 88.0 | 76 | 39 | 33 | 8 | 46 | 77 | 0 | 2 | 1 | 0 | 0 | 1 | 8 | 4.03 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 62 | 0 | 5 | 4 | 3.96 | .274 | 1.11 | 6.7 | 3.2 | 9.2 | 75.0 | 56 | 33 | 33 | 12 | 27 | 77 | 0 | 1 | 0 | 0 | 0 | 2 | 3 | 4.19 |
| RP | Charlton, N.Charlton, Norm >> | 30 | 1993 | L | 31 | 60 | 0 | 5 | 2 | 6.15 | .367 | 1.68 | 10.2 | 5.0 | 9.4 | 67.1 | 76 | 48 | 46 | 9 | 37 | 70 | 0 | 0 | 0 | 0 | 0 | 4 | 8 | 4.49 |