| SP | Kershaw, C.Kershaw, Clayton $$ >> | 28 | 2016 | L | 99 | 24 | 24 | 11 | 7 | 4.02 | .282 | 1.17 | 8.5 | 2.1 | 7.1 | 154.2 | 145 | 74 | 69 | 20 | 36 | 122 | 3 | 0 | 0 | 1 | 14 | 1 | 2 | 3.82 |
| SP | Cole, G.Cole, Gerrit $$ >> | 28 | 2019 | R | 91 | 23 | 23 | 5 | 13 | 5.30 | .334 | 1.48 | 9.9 | 3.5 | 8.1 | 127.1 | 140 | 80 | 75 | 16 | 49 | 115 | 0 | 0 | 0 | 0 | 12 | 3 | 2 | 4.06 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 23 | 23 | 6 | 11 | 5.56 | .304 | 1.31 | 8.9 | 2.9 | 8.0 | 124.2 | 123 | 82 | 77 | 23 | 40 | 110 | 0 | 0 | 0 | 0 | 8 | 0 | 2 | 4.60 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 22 | 22 | 6 | 9 | 5.45 | .335 | 1.48 | 10.3 | 3.0 | 4.3 | 114.0 | 131 | 72 | 69 | 20 | 38 | 54 | 2 | 0 | 0 | 0 | 8 | 3 | 4 | 5.41 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 49 | 0 | 2 | 4 | 2.73 | .258 | 1.03 | 5.7 | 3.6 | 8.7 | 52.2 | 33 | 16 | 16 | 8 | 21 | 50 | 0 | 31 | 4 | 0 | 0 | 1 | 1 | 4.35 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 52 | 0 | 2 | 3 | 3.34 | .271 | 1.10 | 6.8 | 3.1 | 8.7 | 70.0 | 53 | 26 | 26 | 7 | 24 | 68 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.43 |
| SU | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 40 | 0 | 0 | 1 | 3.00 | .262 | 1.02 | 7.1 | 2.1 | 9.6 | 48.0 | 38 | 16 | 16 | 5 | 11 | 51 | 0 | 5 | 3 | 0 | 0 | 2 | 0 | 3.04 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 74 | 44 | 0 | 2 | 3 | 5.47 | .344 | 1.58 | 10.6 | 3.8 | 8.5 | 52.2 | 61 | 34 | 32 | 6 | 22 | 49 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 3.88 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 33 | 0 | 1 | 1 | 3.88 | .261 | 1.06 | 6.1 | 3.5 | 4.3 | 46.1 | 31 | 21 | 20 | 4 | 18 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 4.35 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 8 | 0 | 2 | 0 | 2.79 | .331 | 1.45 | 9.3 | 3.7 | 2.8 | 29.0 | 30 | 10 | 9 | 1 | 12 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.17 |