| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 19 | 19 | 4 | 9 | 5.39 | .329 | 1.40 | 9.3 | 3.3 | 8.4 | 120.1 | 124 | 76 | 72 | 21 | 44 | 112 | 3 | 0 | 0 | 0 | 6 | 9 | 2 | 4.73 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 17 | 17 | 3 | 6 | 7.18 | .367 | 1.71 | 10.9 | 4.7 | 5.0 | 77.2 | 93 | 70 | 62 | 11 | 40 | 43 | 0 | 0 | 0 | 0 | 5 | 2 | 3 | 5.38 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 49 | 0 | 8 | 0 | 3.97 | .302 | 1.29 | 7.2 | 4.4 | 7.3 | 79.1 | 63 | 35 | 35 | 11 | 39 | 64 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.71 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 40 | 0 | 2 | 1 | 2.48 | .260 | 1.05 | 5.9 | 3.6 | 6.2 | 58.0 | 38 | 17 | 16 | 6 | 23 | 40 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 4.16 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 34 | 0 | 3 | 1 | 4.68 | .350 | 1.57 | 7.9 | 6.3 | 6.6 | 67.1 | 59 | 37 | 35 | 6 | 47 | 49 | 0 | 3 | 2 | 0 | 0 | 3 | 2 | 4.94 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 10 | 0 | 0 | 2 | 8.40 | .366 | 1.73 | 13.8 | 1.8 | 9.6 | 15.0 | 23 | 14 | 14 | 3 | 3 | 16 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.07 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 33 | 0 | 4 | 6 | 6.61 | .352 | 1.62 | 11.0 | 3.6 | 6.5 | 80.1 | 98 | 62 | 59 | 20 | 32 | 58 | 0 | 1 | 2 | 0 | 0 | 1 | 2 | 6.04 |