| SP | Tiant, L.Tiant, Luis # $ >> | 28 | 1968 | R | 97 | 32 | 32 | 6 | 18 | 4.27 | .302 | 1.26 | 7.8 | 3.5 | 7.9 | 213.0 | 184 | 110 | 101 | 33 | 84 | 186 | 6 | 0 | 0 | 1 | 16 | 9 | 2 | 4.58 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 32 | 32 | 13 | 10 | 4.30 | .312 | 1.32 | 9.1 | 2.7 | 7.7 | 190.1 | 193 | 98 | 91 | 20 | 58 | 162 | 5 | 0 | 0 | 2 | 15 | 8 | 3 | 3.71 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 31 | 31 | 11 | 9 | 4.43 | .288 | 1.20 | 9.2 | 1.5 | 5.0 | 199.0 | 204 | 102 | 98 | 25 | 34 | 111 | 4 | 0 | 0 | 2 | 13 | 3 | 5 | 4.08 |
| SP | Fernandez, S.Fernandez, Sid # >> | 23 | 1985 | L | 49 | 10 | 9 | 3 | 5 | 5.48 | .313 | 1.36 | 7.1 | 5.4 | 9.2 | 47.2 | 37 | 29 | 29 | 8 | 28 | 48 | 2 | 0 | 0 | 2 | 3 | 0 | 1 | 4.96 |
| CL | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 72 | 0 | 2 | 3 | 2.82 | .304 | 1.28 | 6.7 | 4.9 | 10.3 | 70.1 | 52 | 22 | 22 | 0 | 38 | 80 | 0 | 11 | 1 | 0 | 0 | 2 | 5 | 2.43 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 72 | 0 | 5 | 2 | 2.77 | .295 | 1.23 | 7.4 | 3.8 | 10.4 | 84.1 | 69 | 30 | 26 | 7 | 35 | 97 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 3.10 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 63 | 0 | 5 | 5 | 3.39 | .291 | 1.19 | 7.9 | 2.8 | 10.2 | 77.0 | 68 | 35 | 29 | 9 | 24 | 87 | 0 | 2 | 4 | 0 | 0 | 3 | 0 | 3.31 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 48 | 0 | 6 | 0 | 3.75 | .326 | 1.41 | 8.6 | 4.1 | 6.8 | 50.1 | 48 | 23 | 21 | 6 | 23 | 38 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 4.54 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 29 | 21 | 12 | 7 | 4.77 | .323 | 1.42 | 8.7 | 4.1 | 5.6 | 160.1 | 154 | 91 | 85 | 16 | 73 | 99 | 6 | 0 | 0 | 1 | 11 | 2 | 4 | 4.47 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 18 | 0 | 1 | 0 | 4.66 | .326 | 1.45 | 8.5 | 4.7 | 8.1 | 19.1 | 18 | 11 | 10 | 2 | 10 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.16 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 23 | 0 | 4 | 5 | 3.77 | .277 | 1.15 | 6.4 | 4.0 | 2.4 | 45.1 | 32 | 20 | 19 | 7 | 20 | 12 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 5.82 |