| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 19 | 19 | 5 | 11 | 5.60 | .314 | 1.35 | 8.7 | 3.6 | 7.4 | 109.1 | 105 | 68 | 68 | 22 | 43 | 90 | 3 | 0 | 0 | 0 | 7 | 2 | 1 | 5.21 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 17 | 17 | 8 | 5 | 4.63 | .338 | 1.53 | 10.5 | 3.3 | 4.6 | 103.0 | 120 | 56 | 53 | 13 | 38 | 53 | 3 | 0 | 0 | 0 | 10 | 0 | 2 | 4.72 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 18 | 17 | 2 | 8 | 6.01 | .377 | 1.80 | 11.3 | 4.9 | 6.6 | 91.1 | 114 | 64 | 61 | 11 | 50 | 67 | 2 | 0 | 0 | 0 | 6 | 2 | 5 | 4.81 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 46 | 0 | 3 | 2 | 3.24 | .248 | 0.95 | 7.1 | 1.5 | 8.6 | 66.2 | 52 | 26 | 24 | 6 | 11 | 63 | 0 | 2 | 1 | 0 | 0 | 3 | 2 | 2.91 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 33 | 0 | 2 | 1 | 3.89 | .331 | 1.46 | 6.1 | 7.1 | 9.5 | 37.0 | 25 | 19 | 16 | 3 | 29 | 39 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.38 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 93 | 42 | 0 | 1 | 3 | 3.33 | .281 | 1.15 | 5.4 | 5.1 | 10.7 | 48.2 | 29 | 18 | 18 | 6 | 27 | 57 | 0 | 21 | 5 | 0 | 0 | 1 | 0 | 4.00 |
| RP | Radatz, D.Radatz, Dick >> | 26 | 1963 | R | 19 | 33 | 0 | 3 | 3 | 5.77 | .342 | 1.54 | 8.4 | 5.7 | 7.9 | 57.2 | 53 | 38 | 37 | 12 | 36 | 50 | 0 | 1 | 0 | 0 | 0 | 1 | 3 | 5.93 |