| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 19 | 19 | 8 | 9 | 3.65 | .296 | 1.22 | 7.8 | 3.3 | 6.6 | 130.2 | 113 | 53 | 53 | 13 | 47 | 96 | 2 | 0 | 0 | 1 | 10 | 5 | 0 | 4.02 |
| SP | Richard, J.Richard, J.R. † >> | 30 | 1980 | R | 90 | 18 | 18 | 10 | 3 | 3.20 | .277 | 1.14 | 6.3 | 4.0 | 6.8 | 132.1 | 92 | 47 | 47 | 10 | 59 | 100 | 4 | 0 | 0 | 0 | 12 | 1 | 1 | 3.83 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 18 | 18 | 8 | 8 | 3.38 | .269 | 1.10 | 7.7 | 2.3 | 4.0 | 135.2 | 115 | 54 | 51 | 10 | 34 | 60 | 4 | 0 | 0 | 1 | 12 | 1 | 1 | 3.85 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 17 | 17 | 9 | 4 | 3.64 | .275 | 1.10 | 7.1 | 2.8 | 9.1 | 111.1 | 88 | 50 | 45 | 14 | 34 | 112 | 0 | 0 | 0 | 0 | 9 | 5 | 0 | 3.68 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 17 | 17 | 5 | 8 | 5.79 | .333 | 1.47 | 8.5 | 4.9 | 7.4 | 102.2 | 96 | 66 | 66 | 17 | 55 | 84 | 1 | 0 | 0 | 0 | 6 | 3 | 3 | 5.23 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 57 | 0 | 1 | 0 | 2.08 | .249 | 0.99 | 6.7 | 2.3 | 8.0 | 43.1 | 32 | 10 | 10 | 0 | 11 | 38 | 0 | 6 | 1 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 37 | 0 | 1 | 2 | 3.13 | .277 | 1.07 | 6.6 | 3.2 | 6.6 | 37.1 | 27 | 13 | 13 | 3 | 13 | 27 | 0 | 6 | 2 | 0 | 0 | 3 | 0 | 3.89 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 23 | 0 | 3 | 0 | 1.05 | .313 | 1.32 | 6.5 | 5.8 | 7.6 | 25.2 | 18 | 3 | 3 | 1 | 16 | 21 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.88 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 18 | 0 | 0 | 2 | 3.91 | .225 | 0.83 | 5.1 | 2.3 | 8.6 | 23.0 | 13 | 10 | 10 | 4 | 6 | 22 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.26 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 10 | 0 | 2 | 1 | 2.16 | .286 | 1.20 | 6.8 | 4.5 | 7.9 | 8.1 | 6 | 2 | 2 | 1 | 4 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.38 |