| SP | Leonard, D.Leonard, Dutch $ >> | 22 | 1914 | L | 91 | 18 | 18 | 8 | 5 | 2.41 | .271 | 1.11 | 6.2 | 3.7 | 4.4 | 123.0 | 85 | 35 | 33 | 5 | 51 | 60 | 1 | 0 | 0 | 0 | 15 | 1 | 3 | 3.82 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 18 | 18 | 8 | 4 | 4.65 | .324 | 1.43 | 10.1 | 2.8 | 7.3 | 98.2 | 110 | 52 | 51 | 16 | 31 | 80 | 0 | 0 | 0 | 0 | 5 | 1 | 0 | 4.47 |
| SP | Guidry, R.Guidry, Ron † # >> | 28 | 1978 | L | 77 | 17 | 17 | 13 | 3 | 3.01 | .277 | 1.13 | 7.9 | 2.3 | 5.3 | 128.2 | 113 | 47 | 43 | 8 | 32 | 75 | 5 | 0 | 0 | 1 | 13 | 3 | 0 | 3.46 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 39 | 15 | 15 | 3 | 6 | 6.37 | .324 | 1.41 | 9.5 | 3.3 | 7.9 | 76.1 | 80 | 55 | 54 | 13 | 28 | 67 | 0 | 0 | 0 | 0 | 6 | 2 | 2 | 4.64 |
| RP | Chapman, A.Chapman, Aroldis † >> | 26 | 2014 | L | 93 | 50 | 0 | 4 | 5 | 2.67 | .273 | 1.11 | 6.0 | 3.9 | 9.4 | 64.0 | 43 | 21 | 19 | 3 | 28 | 67 | 0 | 11 | 5 | 0 | 0 | 1 | 4 | 2.88 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 21 | 0 | 1 | 2 | 5.40 | .369 | 1.71 | 9.4 | 6.4 | 9.4 | 21.2 | 22 | 14 | 13 | 1 | 15 | 22 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 3.81 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 9 | 0 | 1 | 0 | 2.57 | .250 | 1.00 | 6.4 | 2.6 | 5.1 | 7.0 | 5 | 2 | 2 | 0 | 2 | 4 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 2.71 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 18 | 0 | 1 | 0 | 3.92 | .308 | 1.33 | 8.1 | 3.9 | 7.2 | 39.0 | 35 | 19 | 17 | 1 | 17 | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.05 |