| SP | Verlander, J.Verlander, Justin >> | 28 | 2011 | R | 92 | 36 | 36 | 19 | 15 | 2.76 | .263 | 1.05 | 6.9 | 2.5 | 5.9 | 261.0 | 201 | 86 | 80 | 16 | 72 | 170 | 12 | 0 | 0 | 6 | 24 | 7 | 7 | 3.40 |
| SP | Newhouser, H.Newhouser, Hal >> | 25 | 1946 | L | 66 | 36 | 36 | 13 | 9 | 4.29 | .310 | 1.33 | 8.2 | 3.8 | 6.3 | 249.2 | 226 | 126 | 119 | 26 | 106 | 173 | 8 | 0 | 0 | 2 | 18 | 4 | 4 | 4.29 |
| SP | Aguirre, H.Aguirre, Hank >> | 31 | 1962 | L | 65 | 35 | 35 | 9 | 10 | 5.21 | .338 | 1.50 | 9.6 | 3.9 | 5.4 | 171.0 | 183 | 108 | 99 | 20 | 74 | 102 | 0 | 0 | 0 | 0 | 13 | 5 | 2 | 4.71 |
| SP | Donovan, B.Donovan, Bill >> | 27 | 1903 | R | 46 | 28 | 28 | 12 | 8 | 5.22 | .322 | 1.38 | 8.9 | 3.4 | 4.4 | 176.0 | 175 | 104 | 102 | 29 | 67 | 86 | 7 | 0 | 0 | 1 | 10 | 9 | 3 | 5.46 |
| SP | Fidrych, M.Fidrych, Mark >> | 22 | 1976 | R | 36 | 27 | 27 | 12 | 8 | 4.43 | .308 | 1.32 | 8.6 | 3.3 | 4.7 | 178.2 | 171 | 97 | 88 | 25 | 65 | 93 | 7 | 0 | 0 | 0 | 10 | 3 | 8 | 4.93 |
| RP | Holton, T.Holton, Tyler >> | 27 | 2023 | L | 82 | 95 | 0 | 3 | 1 | 2.58 | .248 | 0.98 | 6.7 | 2.1 | 3.9 | 101.0 | 75 | 34 | 29 | 12 | 24 | 44 | 0 | 4 | 4 | 0 | 0 | 1 | 4 | 4.42 |
| RP | Hernandez, W.Hernandez, Willie >> | 30 | 1984 | L | 70 | 63 | 0 | 6 | 0 | 1.76 | .210 | 0.80 | 4.3 | 3.0 | 4.3 | 61.1 | 29 | 12 | 12 | 2 | 20 | 29 | 0 | 9 | 1 | 0 | 0 | 0 | 0 | 3.46 |
| RP | Hiller, J.Hiller, John >> | 30 | 1973 | L | 55 | 36 | 0 | 1 | 0 | 3.53 | .301 | 1.21 | 5.7 | 5.4 | 7.5 | 35.2 | 22 | 14 | 14 | 3 | 21 | 29 | 0 | 6 | 2 | 0 | 0 | 3 | 0 | 4.51 |
| RP | Brocail, D.Brocail, Doug >> | 32 | 1999 | R | 48 | 92 | 0 | 6 | 3 | 2.73 | .244 | 0.96 | 6.1 | 2.5 | 6.2 | 85.2 | 58 | 26 | 26 | 4 | 24 | 59 | 0 | 5 | 1 | 0 | 0 | 1 | 4 | 3.11 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 36 | 59 | 0 | 5 | 7 | 5.86 | .331 | 1.45 | 8.0 | 5.1 | 10.0 | 55.1 | 49 | 37 | 36 | 2 | 31 | 61 | 0 | 5 | 2 | 0 | 0 | 2 | 1 | 3.05 |
| RP | Henneman, M.Henneman, Mike >> | 27 | 1988 | R | 21 | 40 | 0 | 5 | 5 | 4.69 | .342 | 1.56 | 9.0 | 5.2 | 5.9 | 40.1 | 40 | 22 | 21 | 4 | 23 | 26 | 0 | 4 | 1 | 0 | 0 | 0 | 6 | 4.73 |
| RP | Lopez, A.Lopez, Aurelio >> | 31 | 1979 | R | 17 | 38 | 0 | 3 | 1 | 4.40 | .325 | 1.38 | 6.8 | 5.6 | 7.0 | 45.0 | 34 | 24 | 22 | 2 | 28 | 35 | 0 | 2 | 1 | 0 | 0 | 3 | 2 | 4.09 |
| SP | Thompson, J.Thompson, Justin >> | 24 | 1997 | L | 30 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | McLain, D.McLain, Denny >> | 25 | 1969 | R | 35 | 4 | 0 | 0 | 1 | 3.60 | .250 | 1.00 | 9.0 | 0.0 | 5.4 | 5.0 | 5 | 2 | 2 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.40 |