| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 28 | 28 | 13 | 10 | 4.27 | .290 | 1.21 | 7.7 | 3.2 | 8.3 | 181.1 | 155 | 90 | 86 | 18 | 65 | 167 | 2 | 0 | 0 | 2 | 15 | 2 | 6 | 3.56 |
| SP | Tudor, J.Tudor, John # >> | 31 | 1985 | L | 63 | 26 | 26 | 10 | 13 | 5.67 | .352 | 1.61 | 11.8 | 2.7 | 5.5 | 173.0 | 227 | 117 | 109 | 20 | 51 | 105 | 2 | 0 | 0 | 0 | 10 | 4 | 2 | 4.24 |
| SP | Coveleski, S.Coveleski, Stan # >> | 28 | 1917 | R | 62 | 26 | 26 | 6 | 9 | 4.70 | .333 | 1.48 | 9.5 | 3.9 | 4.6 | 157.0 | 165 | 92 | 82 | 18 | 68 | 80 | 0 | 0 | 0 | 0 | 12 | 2 | 0 | 4.81 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 56 | 26 | 26 | 7 | 13 | 5.75 | .356 | 1.64 | 10.4 | 4.3 | 4.7 | 164.1 | 190 | 110 | 105 | 13 | 79 | 85 | 2 | 0 | 0 | 1 | 10 | 3 | 4 | 4.49 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 72 | 0 | 6 | 5 | 3.83 | .275 | 1.14 | 6.2 | 4.1 | 8.3 | 105.2 | 72 | 52 | 45 | 13 | 48 | 97 | 0 | 10 | 3 | 0 | 0 | 0 | 1 | 4.13 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 70 | 0 | 4 | 3 | 4.46 | .318 | 1.39 | 8.7 | 3.9 | 9.8 | 80.2 | 77 | 44 | 40 | 7 | 35 | 87 | 0 | 14 | 7 | 0 | 0 | 1 | 3 | 3.31 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 42 | 0 | 3 | 4 | 3.20 | .321 | 1.37 | 9.2 | 3.2 | 9.6 | 56.1 | 57 | 21 | 20 | 6 | 20 | 60 | 0 | 6 | 0 | 0 | 0 | 3 | 0 | 3.48 |
| RP | Sasaki, K.Sasaki, Kazuhiro >> | 33 | 2001 | R | 47 | 32 | 0 | 1 | 0 | 1.62 | .253 | 0.99 | 5.9 | 3.1 | 5.9 | 44.1 | 29 | 8 | 8 | 3 | 15 | 29 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.66 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 6 | 0 | 0 | 0 | 6.91 | .386 | 1.88 | 11.6 | 5.8 | 3.2 | 14.1 | 18 | 11 | 11 | 2 | 9 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.07 |