| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 28 | 28 | 6 | 20 | 4.99 | .328 | 1.45 | 9.6 | 3.4 | 8.7 | 173.0 | 184 | 106 | 96 | 24 | 66 | 167 | 1 | 0 | 0 | 0 | 13 | 3 | 4 | 4.07 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 27 | 27 | 7 | 13 | 6.62 | .352 | 1.62 | 11.3 | 3.2 | 8.8 | 151.0 | 190 | 120 | 111 | 29 | 54 | 148 | 2 | 0 | 0 | 0 | 9 | 2 | 4 | 4.65 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 26 | 26 | 10 | 12 | 4.39 | .309 | 1.31 | 8.7 | 3.2 | 4.8 | 174.1 | 168 | 89 | 85 | 17 | 61 | 93 | 3 | 0 | 0 | 1 | 14 | 5 | 4 | 4.34 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 26 | 26 | 10 | 11 | 4.89 | .319 | 1.38 | 10.2 | 2.3 | 5.2 | 154.2 | 174 | 89 | 84 | 23 | 40 | 89 | 3 | 0 | 0 | 1 | 11 | 3 | 2 | 4.62 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 27 | 26 | 6 | 10 | 4.83 | .328 | 1.42 | 9.3 | 3.5 | 5.4 | 175.0 | 180 | 102 | 94 | 17 | 69 | 105 | 1 | 0 | 0 | 0 | 13 | 7 | 4 | 4.37 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 73 | 0 | 6 | 4 | 2.54 | .256 | 1.03 | 6.0 | 3.3 | 8.5 | 92.0 | 61 | 30 | 26 | 12 | 34 | 87 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 3.91 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 48 | 0 | 1 | 5 | 2.90 | .310 | 1.33 | 7.3 | 4.8 | 11.0 | 49.2 | 40 | 17 | 16 | 4 | 26 | 60 | 0 | 26 | 5 | 0 | 0 | 1 | 0 | 3.27 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 44 | 0 | 3 | 3 | 4.73 | .336 | 1.52 | 7.6 | 6.1 | 8.5 | 53.1 | 45 | 29 | 28 | 6 | 36 | 50 | 0 | 1 | 0 | 0 | 0 | 0 | 6 | 4.62 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 44 | 0 | 1 | 2 | 5.78 | .334 | 1.47 | 8.6 | 4.7 | 4.9 | 81.0 | 77 | 53 | 52 | 9 | 42 | 44 | 0 | 0 | 0 | 0 | 0 | 3 | 7 | 5.02 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 6 | 0 | 1 | 0 | 15.43 | .481 | 2.79 | 24.8 | 4.5 | 2.3 | 4.2 | 11 | 8 | 8 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.50 |