| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 29 | 29 | 9 | 14 | 3.98 | .305 | 1.30 | 9.7 | 2.0 | 8.8 | 167.1 | 180 | 83 | 74 | 17 | 37 | 163 | 0 | 0 | 0 | 0 | 17 | 3 | 0 | 3.09 |
| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 28 | 28 | 11 | 14 | 5.23 | .336 | 1.49 | 9.7 | 3.7 | 4.4 | 170.1 | 184 | 110 | 99 | 25 | 69 | 84 | 2 | 0 | 0 | 0 | 12 | 5 | 3 | 5.23 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 28 | 28 | 12 | 8 | 3.77 | .290 | 1.20 | 8.9 | 2.0 | 5.2 | 188.2 | 185 | 81 | 79 | 13 | 41 | 108 | 8 | 0 | 0 | 3 | 17 | 5 | 2 | 3.48 |
| SP | Reulbach, E.Reulbach, Ed # >> | 24 | 1906 | R | 60 | 26 | 26 | 8 | 11 | 5.97 | .357 | 1.66 | 10.3 | 4.7 | 4.1 | 135.2 | 154 | 96 | 90 | 13 | 71 | 62 | 0 | 0 | 0 | 0 | 10 | 1 | 3 | 4.93 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 26 | 26 | 6 | 12 | 6.43 | .351 | 1.61 | 10.9 | 3.7 | 3.3 | 124.2 | 150 | 89 | 89 | 18 | 51 | 46 | 1 | 0 | 0 | 1 | 7 | 1 | 3 | 5.40 |
| RP | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 76 | 0 | 8 | 1 | 1.45 | .231 | 0.88 | 5.3 | 2.6 | 9.6 | 112.0 | 66 | 21 | 18 | 3 | 32 | 120 | 0 | 9 | 2 | 0 | 0 | 3 | 3 | 2.14 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 62 | 0 | 3 | 7 | 3.70 | .315 | 1.36 | 6.5 | 5.7 | 9.3 | 80.1 | 58 | 33 | 33 | 6 | 51 | 83 | 0 | 5 | 4 | 0 | 0 | 2 | 0 | 3.89 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 64 | 0 | 2 | 2 | 7.95 | .375 | 1.80 | 10.0 | 6.4 | 8.4 | 65.2 | 72 | 59 | 58 | 11 | 46 | 61 | 0 | 7 | 2 | 0 | 0 | 0 | 3 | 5.45 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 45 | 0 | 1 | 0 | 4.22 | .287 | 1.17 | 8.8 | 1.8 | 2.9 | 59.2 | 58 | 28 | 28 | 9 | 12 | 19 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 5.05 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 50 | 22 | 1 | 1 | 4 | 6.55 | .373 | 1.79 | 13.9 | 2.2 | 8.7 | 33.0 | 51 | 26 | 24 | 5 | 8 | 32 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.76 |