| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 97 | 24 | 24 | 11 | 7 | 2.94 | .281 | 1.15 | 6.5 | 3.9 | 7.6 | 174.1 | 126 | 66 | 57 | 13 | 75 | 147 | 4 | 0 | 0 | 1 | 18 | 3 | 2 | 3.63 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 23 | 23 | 6 | 14 | 5.34 | .332 | 1.49 | 10.3 | 3.1 | 4.8 | 175.1 | 200 | 115 | 104 | 22 | 61 | 93 | 8 | 0 | 0 | 0 | 6 | 1 | 4 | 4.63 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 23 | 23 | 8 | 9 | 4.17 | .319 | 1.37 | 8.1 | 4.3 | 3.1 | 146.2 | 132 | 69 | 68 | 14 | 69 | 51 | 1 | 0 | 0 | 1 | 10 | 5 | 0 | 5.07 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 22 | 22 | 5 | 9 | 5.17 | .349 | 1.58 | 10.0 | 4.3 | 4.5 | 135.2 | 150 | 80 | 78 | 11 | 65 | 67 | 1 | 0 | 0 | 0 | 11 | 3 | 7 | 4.58 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 58 | 0 | 2 | 3 | 2.60 | .263 | 1.07 | 6.0 | 3.7 | 8.7 | 83.0 | 55 | 25 | 24 | 9 | 34 | 80 | 0 | 7 | 2 | 0 | 0 | 0 | 0 | 3.71 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 51 | 0 | 4 | 1 | 1.75 | .258 | 1.01 | 4.6 | 4.6 | 7.9 | 67.0 | 34 | 16 | 13 | 2 | 34 | 59 | 0 | 9 | 3 | 0 | 0 | 2 | 1 | 3.24 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 32 | 0 | 2 | 2 | 4.75 | .383 | 1.83 | 10.5 | 6.0 | 9.5 | 36.0 | 42 | 20 | 19 | 3 | 24 | 38 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 4.06 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 29 | 0 | 2 | 3 | 4.65 | .299 | 1.20 | 7.0 | 4.1 | 8.1 | 40.2 | 31 | 22 | 21 | 8 | 18 | 36 | 0 | 4 | 1 | 0 | 0 | 3 | 0 | 5.38 |
| SP | Coombs, J.Coombs, Jack >> | 28 | 1910 | R | 45 | 7 | 0 | 4 | 0 | 3.86 | .288 | 1.21 | 7.1 | 3.9 | 2.6 | 14.0 | 11 | 6 | 6 | 0 | 6 | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.71 |