| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 8 | 8 | 5 | 1 | 2.20 | .243 | 0.95 | 5.8 | 2.8 | 9.1 | 61.1 | 39 | 17 | 15 | 6 | 19 | 62 | 0 | 0 | 0 | 0 | 7 | 1 | 0 | 3.23 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 8 | 8 | 2 | 3 | 5.65 | .314 | 1.35 | 8.8 | 3.3 | 7.1 | 43.0 | 42 | 29 | 27 | 8 | 16 | 34 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 5.02 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 8 | 8 | 4 | 1 | 3.31 | .291 | 1.20 | 7.8 | 3.0 | 5.2 | 54.1 | 47 | 23 | 20 | 4 | 18 | 31 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | 3.93 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 7 | 7 | 3 | 4 | 8.41 | .380 | 1.81 | 12.9 | 3.6 | 6.7 | 35.1 | 50 | 36 | 33 | 7 | 14 | 26 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 5.40 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 7 | 7 | 2 | 3 | 3.86 | .277 | 1.13 | 7.4 | 2.9 | 6.5 | 44.1 | 36 | 21 | 19 | 5 | 14 | 32 | 0 | 0 | 0 | 0 | 3 | 1 | 2 | 4.05 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 21 | 0 | 2 | 0 | 3.29 | .281 | 1.17 | 7.0 | 3.7 | 9.0 | 27.1 | 21 | 12 | 10 | 2 | 11 | 27 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 3.19 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 15 | 0 | 1 | 0 | 5.94 | .315 | 1.32 | 11.3 | 1.1 | 7.9 | 16.2 | 20 | 11 | 11 | 2 | 2 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.44 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 12 | 0 | 0 | 2 | 3.27 | .298 | 1.27 | 8.2 | 3.3 | 4.9 | 11.0 | 10 | 6 | 4 | 3 | 4 | 6 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 6.55 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 17 | 0 | 0 | 0 | 3.31 | .338 | 1.53 | 7.3 | 6.8 | 5.6 | 16.1 | 13 | 8 | 6 | 2 | 12 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.63 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 18 | 0 | 1 | 2 | 3.57 | .303 | 1.30 | 9.0 | 3.2 | 5.8 | 17.2 | 17 | 7 | 7 | 3 | 6 | 11 | 0 | 8 | 1 | 0 | 0 | 0 | 1 | 5.06 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 54 | 8 | 0 | 2 | 0 | 1.15 | .190 | 0.64 | 4.2 | 1.8 | 4.2 | 15.2 | 7 | 2 | 2 | 1 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.73 |