| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 24 | 24 | 9 | 9 | 4.61 | .323 | 1.42 | 9.2 | 3.5 | 8.5 | 166.0 | 170 | 95 | 85 | 17 | 65 | 157 | 2 | 0 | 0 | 0 | 15 | 3 | 4 | 3.67 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 23 | 23 | 9 | 11 | 3.84 | .286 | 1.18 | 8.8 | 1.8 | 5.8 | 166.1 | 163 | 81 | 71 | 11 | 33 | 107 | 7 | 0 | 0 | 1 | 14 | 4 | 1 | 3.24 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 23 | 23 | 4 | 9 | 5.23 | .335 | 1.48 | 10.5 | 2.9 | 4.3 | 118.2 | 138 | 79 | 69 | 18 | 38 | 56 | 0 | 0 | 0 | 0 | 4 | 3 | 2 | 5.08 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 23 | 23 | 7 | 10 | 5.06 | .314 | 1.37 | 9.7 | 2.7 | 4.8 | 154.2 | 166 | 94 | 87 | 24 | 46 | 82 | 4 | 0 | 0 | 0 | 10 | 0 | 1 | 4.86 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 22 | 22 | 6 | 10 | 5.33 | .331 | 1.49 | 10.2 | 3.2 | 4.0 | 136.2 | 154 | 83 | 81 | 12 | 49 | 60 | 2 | 0 | 0 | 0 | 8 | 0 | 1 | 4.35 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 41 | 0 | 3 | 6 | 2.45 | .250 | 0.98 | 5.9 | 2.9 | 10.2 | 44.0 | 29 | 14 | 12 | 5 | 14 | 50 | 0 | 21 | 3 | 0 | 0 | 1 | 1 | 3.23 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 42 | 0 | 0 | 1 | 2.03 | .295 | 1.23 | 6.9 | 4.3 | 9.8 | 48.2 | 37 | 13 | 11 | 2 | 23 | 52 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 2.88 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 55 | 0 | 3 | 2 | 5.05 | .293 | 1.25 | 6.3 | 4.9 | 6.3 | 57.0 | 40 | 33 | 32 | 9 | 31 | 40 | 0 | 2 | 2 | 0 | 0 | 0 | 2 | 5.28 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 80 | 33 | 0 | 1 | 3 | 4.50 | .329 | 1.47 | 9.6 | 3.7 | 8.4 | 32.0 | 34 | 17 | 16 | 4 | 13 | 30 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.97 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 36 | 0 | 6 | 1 | 4.26 | .307 | 1.31 | 8.0 | 3.9 | 6.1 | 44.1 | 39 | 23 | 21 | 5 | 19 | 30 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.48 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 17 | 0 | 0 | 1 | 2.33 | .266 | 1.09 | 6.2 | 3.8 | 8.5 | 19.1 | 13 | 7 | 5 | 3 | 8 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.42 |
| RP | Arroyo, L.Arroyo, Luis >> | 34 | 1961 | L | 11 | 54 | 0 | 3 | 1 | 4.89 | .323 | 1.43 | 8.6 | 4.4 | 6.6 | 49.2 | 47 | 30 | 27 | 4 | 24 | 36 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.06 |