| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 36 | 36 | 20 | 10 | 2.78 | .256 | 1.01 | 7.2 | 2.0 | 8.8 | 249.0 | 198 | 94 | 77 | 25 | 54 | 243 | 3 | 0 | 0 | 2 | 26 | 5 | 0 | 3.06 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 34 | 34 | 16 | 14 | 3.60 | .287 | 1.19 | 7.8 | 2.9 | 7.3 | 249.2 | 216 | 104 | 100 | 25 | 80 | 202 | 9 | 0 | 0 | 1 | 21 | 5 | 4 | 3.71 |
| SP | Arrieta, J.Arrieta, Jake † >> | 29 | 2015 | R | 93 | 33 | 33 | 20 | 7 | 3.00 | .271 | 1.10 | 7.3 | 2.6 | 7.0 | 252.1 | 204 | 88 | 84 | 15 | 73 | 196 | 6 | 0 | 0 | 0 | 24 | 5 | 2 | 3.15 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 84 | 0 | 3 | 3 | 2.86 | .307 | 1.28 | 7.9 | 3.7 | 8.2 | 110.0 | 96 | 40 | 35 | 14 | 45 | 100 | 0 | 18 | 5 | 0 | 0 | 5 | 0 | 4.20 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 52 | 0 | 4 | 6 | 2.85 | .284 | 1.19 | 6.5 | 4.4 | 10.2 | 53.2 | 38 | 18 | 17 | 5 | 26 | 60 | 0 | 11 | 2 | 0 | 0 | 0 | 0 | 3.43 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 17 | 0 | 2 | 0 | 1.29 | .288 | 1.21 | 7.7 | 3.2 | 8.4 | 14.0 | 12 | 2 | 2 | 0 | 5 | 13 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 2.21 |