| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 24 | 24 | 8 | 6 | 3.77 | .304 | 1.31 | 8.8 | 3.0 | 7.5 | 155.1 | 152 | 72 | 65 | 19 | 51 | 130 | 1 | 0 | 0 | 0 | 14 | 1 | 1 | 3.92 |
| SP | Scott, M.Scott, Mike † >> | 31 | 1986 | R | 87 | 24 | 24 | 10 | 9 | 4.04 | .318 | 1.38 | 9.1 | 3.5 | 8.2 | 151.2 | 152 | 71 | 68 | 22 | 58 | 138 | 4 | 0 | 0 | 2 | 13 | 2 | 1 | 4.26 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 23 | 23 | 7 | 9 | 4.70 | .335 | 1.50 | 9.7 | 3.8 | 5.6 | 145.2 | 157 | 86 | 76 | 18 | 61 | 90 | 4 | 0 | 0 | 0 | 11 | 2 | 2 | 4.68 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 79 | 23 | 23 | 9 | 8 | 4.02 | .297 | 1.23 | 8.5 | 2.7 | 7.5 | 132.0 | 124 | 69 | 59 | 17 | 39 | 110 | 0 | 0 | 0 | 0 | 12 | 4 | 3 | 3.98 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 46 | 0 | 0 | 4 | 4.98 | .297 | 1.27 | 7.7 | 3.8 | 11.1 | 43.1 | 37 | 24 | 24 | 5 | 18 | 53 | 0 | 32 | 3 | 0 | 0 | 0 | 2 | 3.30 |
| RP | Kuo, H.Kuo, Hong-Chih † >> | 29 | 2010 | L | 90 | 63 | 0 | 11 | 3 | 1.42 | .254 | 1.02 | 6.0 | 3.2 | 7.4 | 89.0 | 59 | 15 | 14 | 4 | 32 | 73 | 0 | 2 | 2 | 0 | 0 | 0 | 1 | 3.02 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 54 | 0 | 3 | 2 | 4.16 | .291 | 1.23 | 7.7 | 3.5 | 7.1 | 75.2 | 64 | 36 | 35 | 8 | 29 | 59 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 3.97 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 38 | 0 | 4 | 1 | 4.07 | .292 | 1.21 | 8.1 | 2.8 | 7.3 | 42.0 | 38 | 20 | 19 | 5 | 13 | 34 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 3.93 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 32 | 0 | 3 | 1 | 3.78 | .333 | 1.50 | 9.5 | 4.1 | 7.1 | 33.1 | 35 | 15 | 14 | 4 | 15 | 26 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.36 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 21 | 0 | 2 | 1 | 4.58 | .253 | 1.02 | 7.6 | 1.9 | 7.1 | 19.2 | 16 | 10 | 10 | 3 | 4 | 15 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 4.11 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 14 | 0 | 1 | 0 | 3.62 | .281 | 1.17 | 8.0 | 2.7 | 4.7 | 27.1 | 24 | 11 | 11 | 1 | 8 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.33 |