| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 34 | 34 | 11 | 14 | 5.81 | .338 | 1.52 | 10.5 | 3.2 | 8.3 | 217.0 | 253 | 143 | 140 | 35 | 77 | 201 | 2 | 0 | 0 | 1 | 11 | 2 | 3 | 4.34 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 82 | 33 | 33 | 12 | 14 | 5.78 | .343 | 1.54 | 11.6 | 2.2 | 4.5 | 218.0 | 282 | 143 | 140 | 24 | 53 | 109 | 4 | 0 | 0 | 0 | 9 | 7 | 2 | 4.26 |
| SP | Cicotte, E.Cicotte, Eddie † >> | 33 | 1917 | R | 74 | 33 | 33 | 15 | 11 | 5.66 | .354 | 1.62 | 10.8 | 3.9 | 4.1 | 203.2 | 243 | 136 | 128 | 24 | 87 | 92 | 3 | 0 | 0 | 0 | 15 | 5 | 6 | 4.99 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 33 | 31 | 8 | 9 | 5.91 | .341 | 1.55 | 10.3 | 3.7 | 4.3 | 129.1 | 148 | 89 | 85 | 15 | 53 | 61 | 0 | 0 | 0 | 0 | 6 | 0 | 1 | 4.80 |
| RP | Benoit, J.Benoit, Joaquin † >> | 33 | 2010 | R | 95 | 102 | 0 | 8 | 8 | 3.09 | .270 | 1.10 | 7.8 | 2.2 | 8.0 | 148.2 | 128 | 52 | 51 | 19 | 36 | 132 | 0 | 10 | 4 | 0 | 0 | 1 | 2 | 3.64 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 96 | 0 | 8 | 6 | 4.90 | .326 | 1.44 | 8.2 | 4.8 | 6.8 | 125.0 | 114 | 69 | 68 | 15 | 66 | 95 | 0 | 14 | 2 | 0 | 0 | 1 | 4 | 4.65 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 63 | 0 | 2 | 2 | 3.05 | .277 | 1.14 | 6.6 | 3.7 | 8.6 | 82.2 | 60 | 29 | 28 | 7 | 34 | 78 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 3.49 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 49 | 0 | 5 | 0 | 2.51 | .327 | 1.46 | 8.0 | 5.2 | 10.9 | 61.0 | 54 | 18 | 17 | 6 | 35 | 74 | 0 | 2 | 0 | 0 | 0 | 0 | 5 | 3.57 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 55 | 0 | 2 | 4 | 4.44 | .308 | 1.32 | 8.0 | 3.8 | 6.2 | 75.0 | 67 | 40 | 37 | 13 | 32 | 52 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 5.19 |