| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 28 | 28 | 6 | 11 | 5.38 | .323 | 1.40 | 8.9 | 3.7 | 8.7 | 175.2 | 174 | 109 | 105 | 25 | 72 | 169 | 2 | 0 | 0 | 1 | 12 | 6 | 5 | 4.26 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 27 | 26 | 11 | 8 | 4.05 | .311 | 1.35 | 8.3 | 3.9 | 7.6 | 173.1 | 159 | 80 | 78 | 28 | 75 | 147 | 0 | 0 | 1 | 0 | 17 | 1 | 3 | 4.72 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 27 | 27 | 8 | 13 | 5.81 | .307 | 1.32 | 9.1 | 2.7 | 6.4 | 155.0 | 157 | 102 | 100 | 25 | 47 | 110 | 0 | 0 | 0 | 0 | 10 | 2 | 7 | 4.63 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 68 | 0 | 7 | 5 | 3.57 | .308 | 1.31 | 7.3 | 4.6 | 9.2 | 90.2 | 73 | 38 | 36 | 10 | 46 | 92 | 0 | 5 | 3 | 0 | 0 | 2 | 0 | 4.00 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 51 | 0 | 2 | 2 | 3.31 | .314 | 1.34 | 8.5 | 3.7 | 9.0 | 51.2 | 48 | 20 | 19 | 8 | 21 | 51 | 0 | 6 | 1 | 0 | 0 | 2 | 0 | 4.39 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 35 | 0 | 5 | 2 | 3.97 | .282 | 1.18 | 7.1 | 3.4 | 9.5 | 34.0 | 27 | 15 | 15 | 4 | 13 | 36 | 0 | 2 | 2 | 0 | 0 | 0 | 3 | 3.56 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 23 | 0 | 1 | 1 | 2.59 | .291 | 1.23 | 7.5 | 3.8 | 7.9 | 24.1 | 20 | 7 | 7 | 1 | 10 | 21 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.04 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 2 | 2 | 0 | 1 | 6.97 | .380 | 1.84 | 11.7 | 5.4 | 6.3 | 10.1 | 13 | 8 | 8 | 2 | 6 | 7 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 6.00 |