| SP | deGrom, J.deGrom, Jacob † # >> | 37 | 2025 | R | 97 | 24 | 24 | 9 | 8 | 3.27 | .306 | 1.29 | 8.7 | 2.9 | 9.9 | 143.0 | 138 | 55 | 52 | 13 | 46 | 157 | 0 | 0 | 0 | 0 | 17 | 5 | 3 | 3.06 |
| SP | Smith, S.Smith, Shane # >> | 25 | 2025 | R | 72 | 22 | 21 | 4 | 5 | 5.11 | .311 | 1.31 | 8.2 | 3.6 | 9.6 | 88.0 | 80 | 51 | 50 | 10 | 35 | 94 | 0 | 1 | 0 | 0 | 2 | 4 | 3 | 3.67 |
| SP | Gausman, K.Gausman, Kevin >> | 34 | 2025 | R | 81 | 24 | 24 | 11 | 10 | 4.32 | .307 | 1.27 | 8.3 | 3.1 | 8.1 | 152.0 | 140 | 75 | 73 | 20 | 53 | 136 | 1 | 0 | 0 | 1 | 14 | 9 | 2 | 4.14 |
| SP | Cabrera, E.Cabrera, Edward >> | 27 | 2025 | R | 63 | 23 | 23 | 2 | 5 | 4.32 | .351 | 1.57 | 9.7 | 4.4 | 9.9 | 98.0 | 106 | 51 | 47 | 8 | 48 | 108 | 0 | 0 | 0 | 0 | 2 | 5 | 6 | 3.48 |
| SP | Walker, T.Walker, Taijuan >> | 32 | 2025 | R | 7 | 20 | 15 | 2 | 7 | 5.63 | .333 | 1.48 | 10.6 | 2.7 | 8.4 | 56.0 | 66 | 35 | 35 | 12 | 17 | 52 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 4.89 |
| RP | Okert, S.Okert, Steven # >> | 33 | 2025 | L | 97 | 76 | 0 | 6 | 3 | 3.27 | .283 | 1.14 | 7.6 | 2.8 | 10.5 | 71.2 | 60 | 26 | 26 | 6 | 22 | 83 | 0 | 1 | 1 | 0 | 0 | 3 | 0 | 2.82 |
| RP | Holton, T.Holton, Tyler >> | 29 | 2025 | L | 60 | 52 | 0 | 5 | 0 | 1.97 | .241 | 0.95 | 5.8 | 2.9 | 8.1 | 50.1 | 32 | 12 | 11 | 6 | 16 | 45 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 3.72 |
| CL | Bender, A.Bender, Anthony >> | 30 | 2025 | R | 76 | 49 | 0 | 2 | 3 | 1.79 | .278 | 1.11 | 5.8 | 4.3 | 7.4 | 50.1 | 32 | 10 | 10 | 0 | 24 | 41 | 0 | 29 | 4 | 0 | 0 | 2 | 1 | 2.92 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 81 | 62 | 0 | 3 | 1 | 4.30 | .337 | 1.43 | 8.6 | 4.3 | 10.6 | 46.0 | 44 | 29 | 22 | 9 | 22 | 54 | 0 | 1 | 0 | 0 | 0 | 4 | 2 | 4.89 |
| RP | Cantillo, J.Cantillo, Joey >> | 25 | 2025 | L | 48 | 43 | 0 | 7 | 4 | 5.10 | .326 | 1.40 | 8.6 | 4.0 | 11.3 | 72.1 | 69 | 42 | 41 | 13 | 32 | 90 | 0 | 3 | 3 | 0 | 0 | 4 | 0 | 4.35 |
| SP | Flaherty, J.Flaherty, Jack # >> | 29 | 2025 | R | 52 | 14 | 11 | 3 | 4 | 5.40 | .333 | 1.48 | 9.8 | 3.6 | 8.8 | 53.1 | 58 | 32 | 32 | 8 | 21 | 52 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.25 |