| SP | Glasnow, T.Glasnow, Tyler >> | 31 | 2025 | R | 87 | 13 | 13 | 4 | 2 | 3.18 | .296 | 1.22 | 7.2 | 3.9 | 10.4 | 73.2 | 58 | 26 | 26 | 6 | 32 | 84 | 0 | 0 | 0 | 0 | 4 | 3 | 4 | 3.21 |
| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 14 | 13 | 7 | 1 | 3.83 | .295 | 1.21 | 7.8 | 3.1 | 10.1 | 87.0 | 75 | 38 | 37 | 13 | 30 | 98 | 0 | 0 | 0 | 0 | 7 | 4 | 2 | 3.86 |
| SP | Horton, C.Horton, Cade >> | 23 | 2025 | R | 75 | 13 | 13 | 5 | 4 | 4.58 | .340 | 1.51 | 10.8 | 3.0 | 7.2 | 70.2 | 84 | 37 | 36 | 13 | 23 | 56 | 0 | 0 | 0 | 0 | 4 | 2 | 1 | 4.89 |
| SP | Rasmussen, D.Rasmussen, Drew >> | 29 | 2025 | R | 83 | 13 | 13 | 5 | 1 | 2.19 | .266 | 1.04 | 6.3 | 3.1 | 7.6 | 70.0 | 49 | 29 | 17 | 5 | 24 | 59 | 0 | 0 | 0 | 0 | 2 | 3 | 1 | 3.40 |
| SP | Abbott, A.Abbott, Andrew # >> | 26 | 2025 | L | 65 | 13 | 13 | 4 | 4 | 5.26 | .339 | 1.46 | 10.6 | 2.6 | 8.4 | 75.1 | 88 | 46 | 44 | 12 | 22 | 70 | 0 | 0 | 0 | 0 | 4 | 6 | 0 | 4.33 |
| RP | Bednar, D.Bednar, David >> | 30 | 2025 | R | 79 | 35 | 0 | 3 | 2 | 3.00 | .242 | 0.92 | 5.4 | 2.8 | 13.3 | 48.0 | 29 | 16 | 16 | 8 | 15 | 71 | 0 | 2 | 2 | 0 | 0 | 2 | 2 | 3.27 |
| SP | Littell, Z.Littell, Zack >> | 29 | 2025 | R | 59 | 14 | 0 | 3 | 3 | 6.10 | .326 | 1.45 | 10.8 | 2.7 | 6.3 | 20.2 | 24 | 14 | 14 | 3 | 6 | 14 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.45 |