| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 16 | 16 | 7 | 4 | 3.50 | .322 | 1.39 | 7.5 | 5.0 | 9.4 | 105.1 | 88 | 43 | 41 | 8 | 58 | 110 | 0 | 0 | 0 | 0 | 13 | 4 | 3 | 3.67 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 16 | 15 | 5 | 4 | 4.58 | .310 | 1.34 | 8.9 | 3.1 | 4.6 | 110.0 | 109 | 62 | 56 | 15 | 38 | 56 | 1 | 1 | 0 | 1 | 7 | 1 | 5 | 4.82 |
| SU | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 25 | 0 | 0 | 1 | 4.10 | .301 | 1.25 | 9.0 | 2.4 | 8.3 | 26.1 | 26 | 13 | 12 | 2 | 7 | 24 | 0 | 2 | 3 | 0 | 0 | 1 | 1 | 3.08 |
| CL | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 26 | 0 | 2 | 7 | 3.95 | .299 | 1.28 | 9.0 | 2.7 | 9.0 | 27.1 | 27 | 12 | 12 | 3 | 8 | 27 | 0 | 14 | 3 | 0 | 0 | 0 | 0 | 3.33 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 21 | 0 | 3 | 2 | 4.79 | .374 | 1.79 | 11.7 | 5.0 | 12.2 | 20.2 | 26 | 11 | 11 | 4 | 11 | 27 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 4.55 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 16 | 0 | 2 | 1 | 1.93 | .188 | 0.70 | 5.5 | 1.0 | 9.5 | 18.2 | 11 | 6 | 4 | 1 | 2 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1.94 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 17 | 0 | 0 | 0 | 1.21 | .193 | 0.67 | 2.9 | 3.3 | 10.2 | 22.1 | 7 | 3 | 3 | 2 | 8 | 25 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.14 |